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Transporters and Drug-Metabolizing Enzymes in Drug Toxicity
  • Language: en
  • Pages: 530

Transporters and Drug-Metabolizing Enzymes in Drug Toxicity

TRANSPORTERS AND DRUG-METABOLIZING ENZYMES IN DRUG TOXICITY Explore up-to-date coverage on the interaction between drug metabolism enzymes, transporters, and drug toxicity with this leading resources Transporters and Drug-Metabolizing Enzymes in Drug Toxicity delivers a comprehensive and updated review of the relationship between drug metabolism, transporters, and toxicity, providing insights into a major challenge in drug development – accurate assessment of human drug toxicity. Combining two disciplines frequently considered independently of one another, the book combines drug metabolism and toxicology with a focus on the role of biotransformation on drug toxicity and as a major factor f...

The Red Lemon
  • Language: en
  • Pages: 34

The Red Lemon

Farmer McPhee isn't ready for what he's about to discover among his cherished bright yellow fruits . . . a red lemon! Readers young and old will delight in the deliciously vibrant world that acclaimed author-illustrator, Bob Staake, has created. Now available as an affordable Dragonfly paparback!

Memorial Candles: Children of the Holocaust
  • Language: en
  • Pages: 283

Memorial Candles: Children of the Holocaust

  • Type: Book
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  • Published: 2014-02-04
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  • Publisher: Routledge

As the children of the Holocaust reach adulthood, they often need professional help in establishing a new identity and self-esteem. During their childhood their parents have unconsciously transmitted to them much of their own trauma, investing them with all their memories and hopes, so that they become 'memorial candles' to those who did not survive. The book combines verbatim transcriptions of dialogues in individual and group psychotherapy sessions with analyses of dreams, fantasies and childhood memories. Diana Wardi traces the emotional history of her patients, accompanying them on a painful and moving journey into their inner world. She describes the children's infancy in the guilt-laden atmosphere of survivor families, through to their difficult separation from their parents in maturity. she also traces in detail the therapeutic process which culminates in the patients' separation from the role of 'memorial candle'.

Bee Happy
  • Language: en
  • Pages: 42

Bee Happy

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Directory of Brokers and Salesmen
  • Language: en
  • Pages: 874

Directory of Brokers and Salesmen

  • Type: Book
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  • Published: 1952
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  • Publisher: Unknown

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Reactive Drug Metabolites
  • Language: en
  • Pages: 445

Reactive Drug Metabolites

Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the largest pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite toxicity, covering basic concepts and techniques in the process, while the second part details chemical toxicophores that are prone to reactive metabolite formation. This section also reviews the various drug-metabolizing enzymes that can participate in catalyzing reactive metabolite formation, including a discussion of the structure-toxicity relationships for drugs. Two chapters are dedicated to the currently hot topics of her...

Drug Discovery Toxicology
  • Language: en
  • Pages: 598

Drug Discovery Toxicology

As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug safety experiments are both practical and useful • Covers a variety of key topics – safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and –omics tools • Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods • Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices

The Routledge Concise History of Southeast Asian Writing in English
  • Language: en
  • Pages: 512

The Routledge Concise History of Southeast Asian Writing in English

  • Type: Book
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  • Published: 2009-09-10
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  • Publisher: Routledge

The Routledge Concise History of Southeast Asian Writing in English traces the development of literature in the region within its historical and cultural contexts. This volume explores creative writing in English across different genres and media, establishing connections from the colonial activity of the early modern period through to contemporary writing across Southeast Asia, focusing especially on the Philippines, Malaysia, Singapore and Hong Kong. In this critical guide, Rajeev S. Patke and Philip Holden: interweave text and context through the history of creative writing in the region examine language use and variation, making use of illuminating examples from speech, poetry and fictio...

Bee Polite
  • Language: en
  • Pages: 35

Bee Polite

Do you know that BEE-ing POLITE can be fun and easy? When should you say “Excuse me,” “Please” and “Thank you”? At home, in school, at a party or at play, how can you be polite in what you do and what you say? Dee the Bee will show you. For 4-6 year olds, the Dee the Bee series takes the role of a playmate playing teacher. For 3 year olds and below, being read to by an adult contributes to the child's sense of security in his rapidly expanding world.