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Stem Cell Production
This book examines the technologies and processes for the development and commercial production of stem cells according to cGMP guidelines. The initial chapter of the book discusses the therapeutic potentials of stem cells for the treatment of various diseases, including degenerative disorders and genetic diseases. The book then reviews the recent developments in the cultivation of stem cells in bioreactors, including critical cultural parameters, possible bioreactor configuration and integrations of novel technologies in bioprocess developmental stages. The book also introduces microscopic, molecular, and cellular techniques for characterization of stem cells for regulatory approvals. Further, it describes optimal cell transporting conditions to maintain cell viability and properties. Further, it summarizes characterization strategies of clinical grade stem cells for stem cell therapy. This book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells.
Pesticide Toxicology and Risk Assessment
With the emergence of new pesticide combinations and application methods, assessing their potential risks to non-target organisms and human well-being becomes paramount. Pesticide Toxicology and Risk Assessment focuses on the need and strategies for safe and efficient use of pesticides. It offers insights from toxicogenomics, enabling an understanding of the genetic and epigenetic factors influencing human susceptibility to chemical toxicity, thereby quantifying their impacts. This book underscores the significance of risk assessment methodologies considering real-time variables influencing pesticide exposure to the environment and humans. It provides comprehensive details about models desig...
Ethnobotany and Ethnopharmacology of Medicinal and Aromatic Plants
Medicinal and aromatic plants are beneficial to human health. Plant-derived molecules possess biological activities that can be used to prevent many infectious diseases and metabolic disorders. Ethnobotany and Ethnopharmacology of Medicinal and Aromatic Plants summarizes techniques and methods used to study the biological activities of plant-derived extracts and compounds to study ethnobotanical and ethnopharmacological features of medicinal and aromatic plants. This book: Includes computational approaches to study the pharmacological properties of biomolecules in medicinal and aromatic plants. Details methods in ethnopharmacology including chromatographical and analytical techniques. Demons...
The Alzheimer's Disease Challenge
Alzheimer’s disease is undoubtedly the major health challenge of our Century with significant social and economic consequences. This Frontiers eBook offers a contribution of 39 innovative papers on the multidimensional and crucial problem of Alzheimer’s disease management and treatment. Several perspectives, research updates, and trials describing methods on potential diagnosis and treatment are presented including biological mechanisms, biomarkers and risk factors for an early and efficient prognosis, diagnosis and prevention. Additionally, while the rapidly increasing Alzheimer’s disease population demands holistic solutions and clinical studies with new therapeutic target approaches, several of the contributive papers present promising drugs targeting Alzheimer’s disease treatment. We give our deepest acknowledgment to all the authors for their important and innovative contributions, to the reviewers for their valuable recommendations on improving the submitting studies and all the Frontiers Editorial team for continuous support.
Aquatic Macrophytes: Ecology, Functions and Services
This book is a comprehensive collection of information about the features, functions, and services of aquatic macrophytes. As primary producers, aquatic macrophytes form the basis of food webs, play a major role in highly productive aquatic ecosystems, and have a significant impact on ecosystem functions and services. Macrophytes are also known to strongly influence the micro-climate and biogeochemical processes occurring in the littoral zones of marine ecosystems and the sediment dynamics of freshwater systems. They also serve as highly effective carbon sinks and play an important role in carbon sequestration. This book deals with various aspects of aquatic macrophytes, including nutrient r...
Nutrition and Obsessive-Compulsive Disorder
Key features – Covers emerging therapeutic and nutritional approaches for the treatment and management of OCD Reviews the role of various micro-nutrients in OCD Discusses the prenatal genetic diagnosis and application of computational modelling in OCD Includes the nutritional and dietary roles in neuropsychiatric disorders like depression and obsessive-compulsive disorder (OCD) Explores the application of nano-biotechnology in OCD
Honey Bees, Beekeeping and Bee Products
Honey bees are social insects; they live together in large, well-organized family groups comprising three castes: queen (fertile female), workers (sterile females) and drones (males). During honey flow season, there is a considerable increase in the foraging activity of the workers and in the rate of egg laying by the queen. Sex determination in honey bees involves a multi-allelic locus, such that homozygotes develop as males and heterozygotes as females, whereas diet quality influences the caste determination in honey bees. Like all living organisms, honey bees can be infested with diseases and pests. Some of these are more deleterious to bee colonies than others, but it is important for th...
