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Classic Weaponry Of Japan is a Kodansha International publication.
"This extensively illustrated catalogue is published in conjunction with the first comprehensive exhibition devoted to the arts of the samurai, including the finest examples of swords - the spirit of the samurai - as well as sword mountings and fittings, armor and helmets, saddles, textiles, and paintings. The works in the catalogue, drawn from public and private collections in Japan, include 34 officially designated National Treasures and 64 Important Cultural Properties, the largest number ever to be shown together at one time. Dating from the 5th to the early 20th century, these majestic objects offer a complete picture of samurai culture and its unique blend of the martial and the refine...
This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity,solubility, electronic properties and conformation.
The development of the hybridoma technology created the possibility to obtain unlimited amounts of monoclonal antibodies (mAb) with high specificity and affinity for any target and to introduce mAbs in a wide range of applications; however, the bulky size of mAbs, costly production, and cumbersome engineering hampered regularly their streamlined development in some applications. In Single Domain Antibodies: Methods and Protocols, expert researchers examine single variable domain antibody fragments, referred to as VH, VL, VHH or VNAR. These fragments are the smallest intact antigen-binding fragments that can be produced recombinantly at low cost. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
This illuminating study of martial arts techniques, philosophies, and lifestyles demystifies one of the most misunderstood figures in Japanese history—the ninja. A landmark collection of shinobi texts featuring 70 illustrations and 100 poems representing some of the oldest ninjutsu writings in the world The shinobi, or ninja, is one of the most widely recognized figures in the world of espionage—and also one of the most misrepresented. What do we really know about the historical shinobi, his tactics, and his role in medieval Japanese society? In The Secret Traditions of the Shinobi, these questions—and many more—are answered. Translated into English for the very first time, this wide...
In Africa, progress can be seen across the board. But the important question is whether this so-called progress is sustainable. The continent is a powder keg: the powder is demographics and unemployment the detonator. By 2050, the number of young people of working age in Africa is expected to be three times that of China’s. But will there be enough jobs for them? What is troubling for the continent is even more dramatic for the Sahel, a huge region of about 100 million inhabitants where insecurity is spreading like a bushfire. Despite major differences in geography and culture, there are huge similarities between the Sahel and Afghanistan: a demographic impasse, stagnating agriculture, widespread rural misery, high unemployment, deep ethnic and religious fault lines, weak states, regional instability, drug trafficking, and the spread of radical Islam. And unfortunately the same recipes that failed in Afghanistan are being rolled out in the Sahel. Are we headed to a ‘Sahelistan’ and to an ‘Africanistan’? Serge Michailof helps us find the answer to this important question.
A one-stop, practical handbook containing all of the current commercial non-halogenated flame retardant technologies as well as experimental systems near commercialization In response to the emphasis on replacing halogenated flame retardants with alternate technologies, this handbook focuses on existing non-halogenated flame retardants and the experimental close-to-production systems that are available today. The Non-Halogenated Flame Retardant Handbook starts with an overview of the regulations and customer perceptions driving non-halogenated flame retardant selections over older halogenated technologies. It then moves on to cover the known major classes of non-halogenated flame retardants,...
Amebiasis, a parasitic disease transmitted by the unicellular protozoan parasite Entamoeba histolytica, is the cause of at least 100,000 deaths each year. The disease is mostly prevalent in developing countries and is one of the three common causes of death from parasitic diseases. The parasite has two stages in its life cycle in the host: the infective cyst and the invasive trophozoite. In the large intestine, the parasite feeds on bacteria and on cellular debris. No vaccine against amebiasis currently exists. Although metronidazole is the drug of choice for treating amebiasis, adverse effects in patients and potential resistance to metronidazole in other protozoa exist. About nine out of 1...
When first conceived, not only was the aim of Protocols for Oligo nucleotides and Analogs to provide wide coverage of the ohgonuc- otide chemistry field for readers who are well versed within the field, but also to give investigators just entering into the field a new perspective. The very first book on this topic was edited and published by Michael Gait in 1984, in whose laboratory I encountered the newer aspects of oligonucleotide chemistry. Since then, oligonucleotide research has developed to such an extent that its uses extend far beyond basic studies, and now find wide application throughout clinical science as well. Until recently, the major application of oligonucleotides has been in...