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γδ T cells in Cancer
We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). Dr. Dieter Kabelitz currently serves as the chairman for the IUIS Education Committee. Topic Editor Prof. Ilan Bank is Chief Scientific Officer of GammaCell Bio-Technologies Ltd. Topic Editor Prof. Jurgen Kuball is co-founder and scientific advisor of GADETA. Topic Editor Prof. Bruno Silva-Santos is co-founder of Lymphact S.A., a company now owned by GammaDelta Therapeutics. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
The regulation of angiogenesis by tissue cell-macrophage interactions
Angiogenesis is the physiological process where new blood vessels grow from existing ones, in order to replenish tissues suffering from inadequate blood supply. Perhaps the most studied angiogenic process occurs in solid tumors whose growing mass and expanding cells create a constant demand for additional supply of oxygen and nutrients for survival. However, other physiological and clinical conditions, such as wound healing, ischemic events, autoimmune and age-related diseases also involve angiogenesis. Angiogenesis is a well-structured process that begins when oxygen and nutrients are depleted, leading to the release of chemokines and growth factors that attract immune cells, particularly m...
Immunogenic Cell Death in Cancer: From Benchside Research to Bedside Reality
Classically, anti-cancer therapies have always been applied with the primary aim of tumor debulking achieved through widespread induction of cancer cell death. While the role of host immune system is frequently considered as host protective in various (antigen-bearing) pathologies or infections yet in case of cancer overtime it was proposed that the host immune system either plays no role in therapeutic efficacy or plays a limited role that is therapeutically unemployable. The concept that the immune system is dispensable for the efficacy of anticancer therapies lingered on for a substantial amount of time; not only because evidence supporting the claim that anti-cancer immunity played a rol...
Program for the Annual Meeting of the Society for the Study of Reproduction
Includes "Abstracts of papers presented at the annual meeting."
Immune Surveillance
Immune Surveillance deals with the issues regarding tumor immunology and surveillance, in which the central theme is all about the life span of the mammalian host that is depleted by the environment with mutagenic agents and solutions. The book is divided into six chapters. It includes discussions on the organization and modulation of cell membrane receptors, as well as the origin and expression of membrane antigens. It also covers the topics on the triggering mechanisms for and effector mechanisms activated by the cellular recognition. These topics analyze and evaluate alternatives for the recognition and destruction mechanisms in the knowledge of cell cooperation and requirements for immune recognition. A chapter provides discourse on a solution for the paradox of thriving tumors based on the demonstrable in vitro host immunity. Another discusses the generation of antibody diversity and the theory of self-tolerance. The last chapter explains the evaluation of the evidence for immune surveillance. This reference will be invaluable to those who specialize in immunology.
Lopez Island
The story of Lopez Island is a story of community. Skilled, brave, generous people like Sampson Chadwick, Mother Brown, Captain Barlow, and Amelia Davis carved a spirited, nurturing community out of seaside wilderness. Homesteaders cleared forests, built farms, grew food, and raised large families, surviving then thriving together. The hamlets of Port Stanley, Richardson, and Lopez emerged, creating hubs with stores, post offices, and schools as well as thriving fishing, canning, and shipping industries. The community fostered education, music, writing, dances, chivarees, baseball, quilting, a birthday club, and grand Fourth of July celebrations. Living self-reliant lives while helping friends, neighbors, and newcomers, Lopezians created a unique community character that abides today.
Handbook of Performability Engineering
Dependability and cost effectiveness are primarily seen as instruments for conducting international trade in the free market environment. These factors cannot be considered in isolation of each other. This handbook considers all aspects of performability engineering. The book provides a holistic view of the entire life cycle of activities of the product, along with the associated cost of environmental preservation at each stage, while maximizing the performance.
