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Global Clinical Trials for Alzheimer’s Disease
Dementia is seriously disabling for those who have it and is often devastating for their caregivers and families. There are 7.7 million new cases of dementia each year, implying that there is a new case of dementia somewhere in the world every four seconds. The growth of dementia in the next 20 years will be much more acute in those countries with low and medium salaries. The World Health Organization wrote a report about dementia, calling on all governments to define dementia as a public health priority. Dementia clinical studies are becoming more and more complex with the number of enrolled patients increasing. Historically, the majority of patients recruited into clinical trials for medicine development have been from Western Europe and the US. However, clinical trials are increasingly recruiting patients from more countries, including developing countries. South America has larger urban populations than other emerging regions and could provide treatment-naïve patients for clinical trials.
Global Clinical Trials for Alzheimer's Disease
Global Clinical Trials for Alzheimer’s Disease is a handy one-stop reference for researchers and physicians planning and conducting global clinical trials in this area. This book addresses important considerations that may arise during the successful design and execution of these trials, including site selection, local regulatory issues, pharmacogenomics, ethical matters and much more. Given the saturation of traditional clinical trial markets and the worldwide progression of Alzheimer’s disease, there is a need to focus on clinical trials in emerging markets and developing countries. This book provides you with a practical approach to recognizing the opportunities and tackling the chall...
Focus on Meningitis Research
Meningitis is an infection of the fluid of a person's spinal cord and the fluid that surrounds the brain. People sometimes refer to it as spinal meningitis. Meningitis is usually caused by a viral or bacterial infection. Knowing whether meningitis is caused by a virus or bacterium is important because the severity of illness and the treatment differ. Viral meningitis is generally less severe and resolves without specific treatment, while bacterial meningitis can be quite severe and may result in brain damage, hearing loss, or learning disability. For bacterial meningitis, it is also important to know which type of bacteria is causing the meningitis because antibiotics can prevent some types from spreading and infecting other people. Before the 1990s, Haemophilus influenzae type b (Hib) was the leading cause of bacterial meningitis, but new vaccines being given to all children as part of their routine immunizations have reduced the occurrence of invasive disease due to H. influenzae. Today, Streptococcus pneumoniae and Neisseria meningitides are the leading causes of bacterial meningitis.
Further Advances in Pragmatics and Philosophy: Part 2 Theories and Applications
The two sections of this volume present theoretical developments and practical applicative papers respectively. Theoretical papers cover topics such as intercultural pragmatics, evolutionism, argumentation theory, pragmatics and law, the semantics/pragmatics debate, slurs, and more. The applied papers focus on topics such as pragmatic disorders, mapping places of origin, stance-taking, societal pragmatics, and cultural linguistics. This is the second volume of invited papers that were presented at the inaugural Pragmasofia conference in Palermo in 2016, and like its predecessor presents papers by well-known philosophers, linguists, and a semiotician. The papers present a wide variety of perspectives independent from any one school of thought.
Guia de Exercícios para o Cérebro
Para turbinar a memória e ir na contramão das facilidades que engessam a criatividade e não estimulam o raciocínio lógico, reunimos neste guia dicas de alimentação para manter o cérebro nutrido e alerta, além de uma coletânea de atividades de neurobiótica com exercícios para malhar as sinapses cerebrais. Elas ajudarão a melhorar sua capacidade mental, retardando o declínio cognitivo que ocorre naturalmente conforme envelhecemos. Separamos o material por funções mentais, como orientação, atenção, memória, linguagem, raciocínio lógico e praxia. Lembre-se de que as atividades devem ser feitas com calma, em um local tranquilo e silencioso. Os exercícios apresentam diferentes níveis de dificuldade, mas tenha em vista que ao final desta publicação suas habilidades estarão melhores.
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Guia Minha Saúde Especial
Quando alguém de nossa família é diagnosticado com Alzheimer ou Parkinson, muitas dúvidas surgem, tais como: quais são as principais causas e os sintomas mais frequentes; como ter mais qualidade de vida e independência; existem atividades que controlam os estágios das doenças; e como a lei pode beneficiar quem tem o diagnóstico confirmado. Diante de tantos questionamentos, este guia esclarece não somente as dúvidas acima, mas também as melhores e mais atuais ferramentas da medicina para tratar cada uma das doenças, além de dicas de organização na casa, os acessórios que facilitam a vida dos parkinsonianos, as receitas que garantem uma vida mais saudável e a importância de zelar pela saúde e o bem-estar do cuidador.
Minha Saudade E Emoções!
Primeiramente, gostaria de dizer aos meus queridos leitores que estou muito feliz em dividir com vocês um pedacinho de mim, desenvolvi esse trabalho com muito carinho e ao mesmo tempo com muito cuidado, receosa de expor as pessoas que fizeram e que sempre farão parte de minha vida, preservei suas reais identidades com nomes fictícios. São pessoas muito especiais, com as quais compartilhei os melhores momentos de minha infância. Algumas as guardo com muito amor, pois não mais se encontram entre nós. Descrevo a vocês um pouquinho de tudo o que vivi. Ao se deliciarem com minhas lembranças, notarão que tenho muito gosto em descrever fatos pitorescos de minha infância. São momentos qu...
