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Dipeptidyl Aminopeptidases in Health and Disease
Proceedings of the International Conference on Dipeptidyl Aminopeptidases, held September 26-28, 2002, in Berlin, Germany. Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in this field have contributed to this book which presents a state-of-the-art view on these enzymes, at a time when our understanding of their function is growing ever more rapidly and therapeutic options become imminent. The sections of the book focus on various topics: - Structure and function of dipeptidyl aminopeptidases, - DPP IV-like proteins, - Immune mechanisms and immune disorders, - Cancer and angiogenesis, - Diabetes and metabolism, - Therapeutic implications.
ImageScapes
The relationship between different media has emerged as one of the most important areas of research in contemporary cultural and literary studies. But how should we conceive of the relationship between texts and images today? Should we speak of collaboration, interaction or competition? What is the role of literary, historical and scientific texts in a culture dominated by the visual? What is the status of images as cultural artefacts? Are images forms of representation, do they simulate reality or do they intervene in the material world? And how do literature and cultural theory - themselves essentially textual discourses - react to the much-discussed visual turn within Western culture? Does the concept of 'intermediality' allow literary, historical and cultural scholars to envisage a more general theory of media? Addressing these questions from a programmatic point of view, the articles in this volume investigate the effects of different forms of representation in modern European and American literature, media and thought.
Transnational German Studies
This volume consists of a series of essays, written by leading scholars within the field, demonstrating the types of inquiry that can be pursued into the transnational realities underpinning German-language culture and history as these travel right around the globe. Contributions discuss the inherent cross-pollination of different languages, times, places and notions of identity within German-language cultures and the ways in which their construction and circulation cannot be contained by national or linguistic borders. In doing so, it is not the aim of the volume to provide a compendium of existing transnational approaches to German Studies or to offer its readers a series of survey chapter...
Thinking Narratively
What is the connection between philosophical enquiries and storytelling in contemporary narrative? Is it possible to outline some features of a so-called philosophical fiction in Western literature throughout the last two centuries? This book aims to provide a plural answer, hosting extensive essays by seven young researchers coming from different fields (Theory of literature, German, American, Russian and Italian contemporary literature, history and evolution of the essayistic form). A short The volume is addressed to all those with a strong interest in both evolution of philosophical speech and history of the novel and has a strong vocation to promote interdisciplinarity in literary studies.
New Masculinities in Contemporary German Literature
The complex nexus between masculinity and national identity has long troubled, but also fascinated the German cultural imagination. This has become apparent again since the fall of the Iron Curtain and the turn of the millennium when transnational developments have noticeably shaped Germany’s self-perception as a nation. This book examines the social and political impact of transnationalism with reference to current discourses of masculinity in novels by five contemporary male German-language authors. Specifically, it analyses how conceptions of the masculine interact with those of nationality, ethnicity, and otherness in the selected texts and assesses the new masculinities that result from those interactions. Exploring how local discourses of masculinity become part of transnational contexts in contemporary writing, the book moves a consideration of masculinities from a "native" into a transnational sphere.
The Fortunes of Everyman in Twentieth-century German Drama
Death still comes to Everyman, but this study of three twentieth-century German plays shows the harder challenge of living without salvation in an age of war and unprecedented mass destruction. Death comes to everyone, and in the late-medieval morality play of Everyman the familiar skeleton forces the universalized central figure to come to terms with this. Only his inner resources, in the forms of Good Deeds and Knowledge, ensure that he repents and is redeemed. Three important twentieth-century German plays echo Everyman - Toller's Hinkemann, Borchert's The Man Outside, and Frisch's The Arsonists/Firebugs - but the unprecedented scale of killing in the First and Second World Wars changed t...
Thinking in Constellations
With his powerful thought image of the constellation, Walter Benjamin provides a method for the core practices of the Humanities: reading, writing, and thinking. This collection of provocative essays demonstrates how thinking in constellations with Walter Benjamin leads us towards a new understanding of the critical task of the Humanities today: it goes beyond disciplinary boundaries and challenges assumptions of linearity, coherence, and progression inherent in our scholarly praxis. The volume brings some of the most articulate young voices in international Benjamin scholarship together, and takes an interdisciplinary approach, covering wide-ranging fields of knowledge – quantum physics, postcolonial studies, natural philosophy, psychoanalysis, film theory, literature, and the arts. Benjamin’s texts are re-considered in light of thinkers and poets, such as Theodor W. Adorno, Sigmund Freud, Gottfried E. Leibniz, W. G. Sebald, Franz Kafka, or Carlos Martínez Rivas. The critical potential of constellations in Benjamin’s work and beyond will be of the highest interest for researchers and students in all areas of the Humanities.
Redeeming Words
Probing study of how literature can redeem the revelatory, redemptive powers of language. In this probing look at Alfred Döblin’s 1929 novel Berlin Alexanderplatz and the stories of W. G. Sebald, Redeeming Words offers a philosophical meditation on the power of language in literature. David Kleinberg-Levin draws on the critical theory of Benjamin and Adorno; the idealism and romanticism of Kant, Hegel, Hölderlin, Novalis, and Schelling; and the nineteenth- and twentieth-century thought of Nietzsche, Heidegger, and Derrida. He shows how Döblin and Sebald—writers with radically different styles working in different historical moments—have in common a struggle against forces of negativity and an aim to bring about in response a certain redemption of language. Kleinberg-Levin considers the fast-paced, staccato, and hard-cut sentences of Döblin and the ghostly, languorous, and melancholy prose fiction of Sebald to articulate how both writers use language in an attempt to recover and convey this utopian promise of happiness for life in a time of mourning.
Revelations of Humanity
Revelations of Humanity brings together essays into the history and actuality of how our searches for God and for our own humanity are interwoven. They argue that the revelation of God is possible only when accompanied by a revelation of what it means to be a human being. Revelation implies that the truth is not fully evident in either case. This quest is aided in many of the essays by a recollection of the thought of Thomas Aquinas. As opposed to simple memory, recollection implies that memory has been lost or become clouded, here by the misrepresentation of Thomas’ view of humanity’s relation to God as harmonistic, at best semi-Pelagian, often even naturalistic. This difficult recovery...
