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Current Challenges in Complement Diagnostics
The complement system is an important innate immune surveillance network that has a key role in protecting our bodies against pathogens and other threats. It is a highly complex system consisting of approximately 50 soluble and cell surface-bound proteins that interact to eliminate danger signals. These signals include factors such as invading microorganisms, necrotic cells, and immune complexes. Furthermore, complement can link innate and adaptive immune responses by regulating T cell and B cell responses. The complement system is tightly regulated to avoid uncontrolled activation. Dysregulation of the complement system has been linked to numerous diseases, both rare and common. Uncontrolle...
Tilhi
Hurja ja herkkä esikoisromaani hylätyiksi tulleista ja rakkaudettomuuden runtelemista Karoliina Niskasen esikoisromaani Tilhi on kertomus unohdetuiksi tulleista ihmisistä ja rikkinäisistä perheistä. Inkeri Suominen istuu parvekkeella, ja hänen vastasyntynyt vauvansa nukkuu päiväunia. Juuri tänään on sopiva päivä aloittaa, harmaa ja lokkien kirkunan kyllästämä. Tänään Inkeri avaa läppärin ja alkaa kirjoittaa. Hänen on päästävä kertomaan tarinansa sille, joka voisi auttaa löytämään Tilhin, hänen kadonneen pikkuveljensä. Tilhi tuli osaksi Suomisen perheen elämää heiveröisenä ja hauraana sijoituslapsena, vähän omituisena linnunpoikana, jolla oli oranssi ir...
Slavery, Agriculture, and Malaria in the Arabian Peninsula
In Slavery, Agriculture, and Malaria in the Arabian Peninsula, Benjamin Reilly illuminates a previously unstudied phenomenon: the large-scale employment of people of African ancestry as slaves in agricultural oases within the Arabian Peninsula. The key to understanding this unusual system, Reilly argues, is the prevalence of malaria within Arabian Peninsula oases and drainage basins, which rendered agricultural lands in Arabia extremely unhealthy for people without genetic or acquired resistance to malarial fevers. In this way, Arabian slave agriculture had unexpected similarities to slavery as practiced in the Caribbean and Brazil. This book synthesizes for the first time a body of historic...
History of Nordic Computing 2
The First Conference on the History of Nordic Computing (HiNC1) was organized in Trondheim, in June 2003. The HiNC1 event focused on the early years of computing, that is the years from the 1940s through the 1960s, although it formally extended to year 1985. In the preface of the proceedings of HiNC1, Janis Bubenko, Jr. , John Impagliazzo, and Arne Sølvberg describe well the peculiarities of early Nordic c- puting [1]. While developing hardware was a necessity for the first professionals, quite soon the computer became an industrial product. Computer scientists, among others, grew increasingly interested in programming and application software. P- gress in these areas from the 1960s to the ...
Arto Salomaa: Mathematician, Computer Scientist, and Teacher
This book outlines the scientific career of Arto Salomaa, a pioneer in theoretical computer science and mathematics. The author first interviewed the subject and his family and collaborators, and he then researched this fascinating biography of an intellectual who was key in the development of these fields. Early chapters progress chronologically from Academician Salomaa's origins, childhood, and education to his professional successes in science, teaching, and publishing. His most impactful direct research efforts have been in the areas of automata and formal languages. Beyond that he has influenced many more scientists and professionals through collaborations, teaching, and books on topics...
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