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Role of Stem Cells in Skeletal Muscle Development, Regeneration, Repair, Aging and Disease
Adult stem cells are responsible for tissue regeneration and repair throughout life. Their quiescence or activation are tightly regulated by common signalling pathways that often recapitulate those happening during embryonic development, and thus it is important to understand their regulation not only in postnatal life, but also during foetal development. In this regard, skeletal muscle is an interesting tissue since it accounts for a large percentage of body mass (about 40%), it is highly amenable to intervention through exercise and it is also key in metabolic and physiological changes underlying frailty susceptibility in the elderly. While muscle-resident satellite cells are responsible f...
Pericyte Biology in Disease
This volume explores pericytes' roles under distinct pathological conditions, ranging from tumors, ALS, Alzheimer’s disease, Multiple Sclerosis, stroke, diabetes, atherosclerosis, muscular dystrophies and more. Together with its companion volumes Pericyte Biology in Different Organs and Pericyte Biology – Novel Concepts, Pericyte Biology in Disease presents a comprehensive update on the latest information and most novel functions attributed to pericytes. To those researchers newer to this area, it will be useful to have the background information on these cells' unique history. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cell biology and clinicians involved with these specific diseases.
Wound Healing
A comprehensive resource on the recent developments of stem cell use in wound healing With contributions from experts in the field, Wound Healing offers a thorough review of the most recent findings on the use of stem cells to heal wounds. This important resource covers both the basic and translational aspects of the field. The contributors reveal the great progress that has been made in recent years and explore a wide range of topics from an overview of the stem cell process in wound repair to inflammation and cancer. They offer a better understanding of the identities of skin stem cells as well as the signals that govern their behavior that contributes to the development of improved therap...
The Nidoviruses
In 1996 the International Committee for Taxonomy of Viruses (ICTV) recognized the name Nidovirales, as the formal name for Coronaviridae and A rteriviridae. In recognition of this change, and in response to the wishes of our colleagues we named this meeting for the first time "The International Symposium of Nidoviruses". The meeting in the wooded environment of Lake Harmony, Pennsylvania, provided a stimulating opportunity for assessing the progress made in the field since the last meeting in Segovia Spain in 1997. Over 150 scientists from academia and industry attended the meeting. The meeting hosted senior members of the Nidovirus community, some of whom have been studying the subject for ...
Wow in the World: the How and Wow of the Human Body
A #1 New York Times Bestseller! Based on their #1 kids podcast, Wow in the World, hosts Mindy Thomas and Guy Raz take readers on a hilarious, fact-filled, and highly illustrated journey through the human body--covering everything from our toes to our tongues to our brains and our lungs! WHY in the world do I have a belly button? And WHAT in the world does it do? WHEN in the world will my nose stop growing? And HOW in the world does my pee keep flowing? The human body is a fascinating piece of machinery. It's full of mystery, and wonder, and WOW. And it turns out, every single human on the planet has one! Join Mindy Thomas and Guy Raz, hosts of the mega-popular Wow in the World podcast, as they take you on a fact-filled adventure from your toes and your tongues to your brain and your lungs. Featuring hilarious illustrations and filled with facts, jokes, photos, quizzes, and Wow-To experiments, The How and Wow of the Human Body has everything you need to better understand your own walking, talking, barfing, breathing, pooping body of WOW!
Stimuli-Responsive Materials for Tissue Engineering
Enables advanced tissue regeneration approaches via expertise from the fields of materials science and biology Stimuli-Responsive Materials for Tissue Engineering comprehensively reviews the use of stimuli-responsive materials in the context of advanced tissue engineering approaches, highlighting applications, challenges, and solutions and reporting on the current state of the art of smart and multifunctional materials being used for tissue engineering, focusing on material types and their properties. The progress that has already been achieved in the field is put into perspective by covering the remaining challenges in the research field of tissue engineering, and solutions are outlined to ...
Sarcopenia
Sarcopenia: Molecular, Cellular, and Nutritional Aspects describes the progressive loss of skeletal muscle mass and strength, defined by Rosenberg in 1997 as a hallmark of aging and referred to as “sarcopenia.” As life expectancy continues to increase worldwide, sarcopenia has become a major public health issue. The condition worsens in the presence of chronic diseases accelerating its progression. Sarcopenia is not considered to be “a process of normative aging” but according to the International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM), as a disease. As sarcopenia is an ineluctable process, prevention and management are the only options to promot...
