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High-density Lipoprotein Function is Modulated by the SARS-CoV-2 Spike Protein in a Lipid-type Dependent Manner
Abstract: There is a close relationship between the SARS-CoV-2 virus and lipoproteins, in particular high-density lipoprotein (HDL). The severity of the coronavirus disease 2019 (COVID-19) is inversely correlated with HDL plasma levels. It is known that the SARS-CoV-2 spike (S) protein binds the HDL particle, probably depleting it of lipids and altering HDL function. Based on neutron reflectometry (NR) and the ability of HDL to efflux cholesterol from macrophages, we confirm these observations and further identify the preference of the S protein for specific lipids and the consequent effects on HDL function on lipid exchange ability. Moreover, the effect of the S protein on HDL function diff...
The St. Lucia Island Club
When retired Southern sheriff-turned-New York City detective John Le Brun and his wife, Lordis, set sail in 1910 for a long-awaited honeymoon on the Caribbean island of St. Lucia, they expect to find relaxation in paradise. However, they soon discover they’ve been lured to the island in part to tout its attributes as a burgeoning vacation retreat to wealthy investors back home. Instead of finding tranquility among the tropical isle’s quaint villages and sandy beaches, they encounter a land teeming with racial, social, and economic tension. The brutal murders of a local plantation owner’s family find John putting his renowned detective skills to use, with Lordis readily playing assistan...
Vigée Le Brun
Elisabeth Louise Vigée Le Brun (1755–1842) was one of the finest eighteenth-century french painters and among the most important women artists of all time. Celebrated for her expressive portraits of French royalty and aristocracy, and especially of her patron Marie Antoinette, Vigée Le Brun exemplified success and resourcefulness in an age when women were rarely allowed either. Because of her close association with the queen Vigée Le Brun was forced to flee France during the French Revolution. For twelve years she traveled throughout Europe, painting noble sitters in the courts of Naples, Russia, Austria, and Prussia. She returned to France in 1802, under the reign of Emperor Napoleon I...
Academies of Art
Met teksten in het Engels, Frans, Italiaans, Duits, Nederlands Bibliografie : p. 561-590 Recent investigations conceiving the history of the education of young artists, and the theories of art connected with that education.
ArtCurious
A wildly entertaining and surprisingly educational dive into art history as you've never seen it before, from the host of the beloved ArtCurious podcast We're all familiar with the works of Claude Monet, thanks in no small part to the ubiquitous reproductions of his water lilies on umbrellas, handbags, scarves, and dorm-room posters. But did you also know that Monet and his cohort were trailblazing rebels whose works were originally deemed unbelievably ugly and vulgar? And while you probably know the tale of Vincent van Gogh's suicide, you may not be aware that there's pretty compelling evidence that the artist didn't die by his own hand but was accidentally killed--or even murdered. Or how ...
