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High-density Lipoprotein Function is Modulated by the SARS-CoV-2 Spike Protein in a Lipid-type Dependent Manner
  • Language: en

High-density Lipoprotein Function is Modulated by the SARS-CoV-2 Spike Protein in a Lipid-type Dependent Manner

  • Type: Book
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  • Published: 2023
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  • Publisher: Unknown

Abstract: There is a close relationship between the SARS-CoV-2 virus and lipoproteins, in particular high-density lipoprotein (HDL). The severity of the coronavirus disease 2019 (COVID-19) is inversely correlated with HDL plasma levels. It is known that the SARS-CoV-2 spike (S) protein binds the HDL particle, probably depleting it of lipids and altering HDL function. Based on neutron reflectometry (NR) and the ability of HDL to efflux cholesterol from macrophages, we confirm these observations and further identify the preference of the S protein for specific lipids and the consequent effects on HDL function on lipid exchange ability. Moreover, the effect of the S protein on HDL function diff...

Membrane Structure and Dynamics Studied With Neutron Scattering
  • Language: en
  • Pages: 134
All the Beauty in the World
  • Language: en
  • Pages: 240

All the Beauty in the World

  • Categories: Art

"A fascinating, revelatory portrait of the Metropolitan Museum of Art and its treasures by a former New Yorker staffer who spent a decade as a museum guard"--

Pharmaceutical Nanotechnology, 2 Volumes
  • Language: en
  • Pages: 804

Pharmaceutical Nanotechnology, 2 Volumes

Dieses Fachbuch legt den Schwerpunkt auf konkrete Methoden und die jüngsten Fortschritte bei der Anwendung von Nanotechnologie für die Entwicklung neuer medikamentöser Therapieansätze und die medizinische Diagnostik. Von den Grundlagen der Nanopharmazie, einschließlich Charakterisierung und Herstellungsverfahren, bis hin zur Rolle von Nanopartikeln und Wirkstoffen wird das Fachgebiet umfassend dargestellt. Anwendungsbeispiele beziehen sich auf Fragestellungen bei der Medikamentenentwicklung und die Übertragung auf die klinische Praxis, Marktchancen und Aspekte der industriellen Vermarktung. Die beschriebenen Anwendungen stammen aus der Behandlung von Krebserkrankungen und weiteren wichtigen Therapiebereichen wie Infektionskrankheiten und Dermatologie. Abgerundet wird das Fachbuch durch eine ausführliche Erörterung sicherheitsrelevanter, rechtlicher und gesellschaftlicher Fragen. Geschrieben von einem erstklassigen Team von Herausgebern und Autoren, die zu den führenden Experten in Europa und den USA sowie zu den Pionieren der Nanopharmazie gehören.

Function and Dysfunction of Complement Factor H
  • Language: en
  • Pages: 175

Function and Dysfunction of Complement Factor H

None

Isotope Labeling of Biomolecules – Applications
  • Language: en
  • Pages: 513

Isotope Labeling of Biomolecules – Applications

Isotope Labeling of Biomolecules: Applications, the latest in the Methods in Enzymology series, focuses on stable isotope labeling methods and applications for biomolecules. This practical guide to biomolecular labeling looks at new techniques that are becoming widely used. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Focuses on stable isotope labeling of biomolecules, which is important for structural studies of proteins and nucleic acids

Isotope Labeling of Biomolecules – Labeling Methods
  • Language: en
  • Pages: 662

Isotope Labeling of Biomolecules – Labeling Methods

Isotope Labeling of Biomolecules – Labeling Methods, the latest volume of the Methods in Enzymology series contains comprehensive information on stable isotope labeling methods and applications for biomolecules. - Contains contributions from leading authorities in the field of isotope labeling of biomolecules - Informs and updates on the latest developments in the field - Provides comprehensive information on stable isotope labeling methods and applications for biomolecules

Pennsylvania German Marriages
  • Language: en
  • Pages: 620

Pennsylvania German Marriages

None

Asian American Film Festivals
  • Language: en
  • Pages: 350

Asian American Film Festivals

Responding to a lack of studies on the film festival’s role in the production of cultural memory, this book explores different parameters through which film festivals shape our reception and memories of films. By focusing on two Asian American film festivals, this book analyzes the frames of memory that festivals create for their films, constructed through and circulated by the various festival media. It further establishes that festival locations—both cities and screening venues—play a significant role in shaping our experience of films. Finally, it shows that festivals produce performances which help guide audiences towards certain readings and direct the film’s role as a memory ob...