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Este compilado de patologias do sistema imune traz um enfoque clínico e laboratorial essencial para o diagnóstico de doenças e fenômenos imunes prevalentes na população. O intuito deste livro é auxiliar estudantes da área da saúde a entender melhor onde os conceitos de imunologia básica se aplicam na rotina clínica. Além disso, os temas são abordados de maneira sucinta e objetiva, ideais para revisão rápida de pontos importantes no que se refere aos estudos das doenças aqui abordadas, principalmente as de caráter autoimune.
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This book offers a detailed review of the remarkable advances that have been made in research on the pathogenesis of a number of neuroimmunological diseases, as well as outlining novel treatments including the use of monoclonal antibodies. Written by renowned experts who have made major contributions in the field, such as identifying neuromyelitis optica as an immunopathological clinical condition, identifying the role of ganglioside and ganglioside-complex antibodies in Guillain-Barré syndrome, and developing a novel treatment for POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome, the book summarizes recent advances in basic and clinical research. Neuroimmunological Diseases is a useful resource for not only researchers but also neurologists who are engaged in the management of neuroimmunological diseases.
Widely considered the greatest genius of all time, Albert Einstein revolutionised our understanding of the cosmos with his general theory of relativity and helped to lead us into the atomic age. Yet in the final decades of his life he was also ignored by most working scientists, his ideas opposed by even his closest friends. This stunning downfall can be traced to Einstein's earliest successes and to personal qualities that were at first his best assets. Einstein's imagination and self-confidence served him well as he sought to reveal the universe's structure, but when it came to newer revelations in the field of quantum mechanics, these same traits undermined his quest for the ultimate truth. David Bodanis traces the arc of Einstein's intellectual development across his professional and personal life, showing how Einstein's confidence in his own powers of intuition proved to be both his greatest strength and his ultimate undoing. He was a fallible genius. An intimate and enlightening biography of the celebrated physicist, Einstein's Greatest Mistake reveals how much we owe Einstein today - and how much more he might have achieved if not for his all-too-human flaws.
An assemblage of extracts from the complete works of Charles Dickens, including his speeches. The volume reflects the editor's effort to include every notable/quotable passage or short comment by Dickens on a subject which interested the great author. It contains over 860,000 words, and there are over 50 illustrations. Included are 27 extended extracts, largely from the fictional works, which capture the greatest scenes in the oeuvre, including the trial of Bardell v. Pickwick, Ralph Nickleby's frustration and suicide, Jonas Chuzzlewit's murder of Tigg Montague and its aftermath, and Mr. Micawber's demolishment of Uriah Heep. This reference has over 405 topic captions, or subject headings, o...
This book addresses the emerging paradigm of data-driven engineering design. In the big-data era, data is becoming a strategic asset for global manufacturers. This book shows how the power of data can be leveraged to drive the engineering design process, in particular, the early-stage design. Based on novel combinations of standing design methodology and the emerging data science, the book presents a collection of theoretically sound and practically viable design frameworks, which are intended to address a variety of critical design activities including conceptual design, complexity management, smart customization, smart product design, product service integration, and so forth. In addition, it includes a number of detailed case studies to showcase the application of data-driven engineering design. The book concludes with a set of promising research questions that warrant further investigation. Given its scope, the book will appeal to a broad readership, including postgraduate students, researchers, lecturers, and practitioners in the field of engineering design.
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"Brazil was the leading world producer of gold and of diamonds between the mid-18th century and the mid-19th century. At the present time, it is the leading world producer of iron ore, tin and niobium, and an important producer of manganese, aluminium, silicon, tantalum, rare earths, graphite, magnesite and countless other ores.....Brazil is the leading world producer of tourmaline (of all colors), of quartz (colorless, rutilated, amethyst and agate), of beryl (aquamarine, morganite and heliodore, and the second ranking world producer of emerald), of topaz (imperial, blue and colorless), alexandrite, euclase, phenakite and many others" INTRODUCTION.
The edited book Pesticides - Toxic Aspects contains an overview of attractive researchers of pesticide toxicology that covers the hazardous effects of common chemical pesticide agents employed every day in our agricultural practices. The combination of experimental and theoretical pesticide investigations of current interest will make this book of significance to researchers, scientists, engineers, and graduate students who make use of those different investigations to understand the toxic aspects of pesticides. We hope that this book will continue to meet the expectations and needs of all interested in different aspects of pesticide toxicity.
500 Cookies truly is the only cookie compendium you'll ever need. With this second edition, home cooks will find 150 scrumptious new receipes that are sure to be crowd pleasers. New recipes include tasty ingredient combinations such as Peanut butter amp; Praline Chunk Swirl cookies, Chocolate amp; Lemon Pinwheel Cookies, and Coconut amp; Cherry Macaroons.