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Este compilado de patologias do sistema imune traz um enfoque clínico e laboratorial essencial para o diagnóstico de doenças e fenômenos imunes prevalentes na população. O intuito deste livro é auxiliar estudantes da área da saúde a entender melhor onde os conceitos de imunologia básica se aplicam na rotina clínica. Além disso, os temas são abordados de maneira sucinta e objetiva, ideais para revisão rápida de pontos importantes no que se refere aos estudos das doenças aqui abordadas, principalmente as de caráter autoimune.
This book provides a comprehensive overview of the patterns of biodiversity in various neotropical ecosystems, as well as a discussion on their historical biogeographies and underlying diversification processes. All chapters were written by prominent researchers in the fields of tropical biology, molecular ecology, climatology, paleoecology, and geography, producing an outstanding collection of essays, synthetic analyses, and novel investigations that describe and improve our understanding of the biodiversity of this unique region. With chapters on the Amazon and Caribbean forests, the Atlantic rainforests, the Andes, the Cerrado savannahs, the Caatinga drylands, the Chaco, and Mesoamerica – along with broad taxonomic coverage – this book summarizes a wide range of hypotheses, views, and methods concerning the processes and mechanisms of neotropical diversification. The range of perspectives presented makes the book a truly comprehensive, state-of-the-art publication on the topic, which will fascinate both scientists and general readers alike.
This book continues from where the authors' previous book, Structural Proof Theory, ended. It presents an extension of the methods of analysis of proofs in pure logic to elementary axiomatic systems and to what is known as philosophical logic. A self-contained brief introduction to the proof theory of pure logic is included that serves both the mathematically and philosophically oriented reader. The method is built up gradually, with examples drawn from theories of order, lattice theory and elementary geometry. The aim is, in each of the examples, to help the reader grasp the combinatorial behaviour of an axiom system, which typically leads to decidability results. The last part presents, as an application and extension of all that precedes it, a proof-theoretical approach to the Kripke semantics of modal and related logics, with a great number of new results, providing essential reading for mathematical and philosophical logicians.
"In this book, Ola Wikander studies Indo-European influences in the literary world of the Hebrew Bible and the Ugaritic texts, tracing a number of poetic motifs and other concepts originating in the Indo-European linguistic milieux of the greater Ancient Near East (e.g., among Anatolians and in Indo-European traditions transmitted through Mitanni)--and possibly at earlier, reconstructible levels--as they influenced what became Northwest Semitic poetic culture. The methodology used is what Wikander refers to as "etymological poetics": the study of poetic and mythological structures as transmitted through specific lexical material. One of the motifs discussed is that of destroying heat being used as a metaphor for forgetting important cultural memories and, consequently, of the resilience of such memories being expressed as resistance to burning. Thus, bringing these ancient connections between Indo-European and Northwest Semitic culture into the open is, in a sense, showing their "Unburning Fame"--
The Hornbooks of Rita K, Robert Kroetsch's first volume of new poetry in more than a decade, is a brilliant collection of mysterious fragments. Where has Rita gone and who is reconstructing her oeuvre? Written with wit and playfulness, Hornbooks is a welcome new work from one of Canada's best writers.
This book presents an evolutionary biogeographic analysis of the Mexican Transition Zone, which is situated in the overlap of the Nearctic and Neotropical regions. It includes a comprehensive review of previous track, cladistic and molecular biogeographic analyses and is illustrated with full color maps and vegetation photographs of the respective areas covered. Given its scope, the book will be of interest to students and researchers whose work involves systematic and biogeographic analyses of plant and animal taxa of the Mexican Transition Zone or other transition zones of the world, and to ecologists working in biodiversity conservation, who will be able to appreciate the evolutionary relevance of the Mexican Transition Zone for establishing conservation areas..
The book aims to provide an introduction to mathematical models that describe the dynamics of tumor growth and the evolution of tumor cells. It can be used as a textbook for advanced undergraduate or graduate courses, and also serves as a reference book for researchers. The book has a strong evolutionary component and reflects the viewpoint that cancer can be understood rationally through a combination of mathematical and biological tools. It can be used both by mathematicians and biologists. Mathematically, the book starts with relatively simple ordinary differential equation models, and subsequently explores more complex stochastic and spatial models. Biologically, the book starts with explorations of the basic dynamics of tumor growth, including competitive interactions among cells, and subsequently moves on to the evolutionary dynamics of cancer cells, including scenarios of cancer initiation, progression, and treatment. The book finishes with a discussion of advanced topics, which describe how some of the mathematical concepts can be used to gain insights into a variety of questions, such as epigenetics, telomeres, gene therapy, and social interactions of cancer cells.
More often than not, when people think of a neotropical forest, what comes to mind is a rain forest, rather than a dry forest. Just as typically, when they imagine a savanna, they visualize the African plains, rather than those dry woodlands and grasslands found in the Neotropics. These same preconceptions can be found among scientists, as these ne
To unravel the complex shared history of the Earth and its life forms, biogeographers analyze patterns of biodiversity, species distribution, and geological history. So far, the field of biogeography has been fragmented into divergent systematic and evolutionary approaches, with no overarching or unifying research theme or method. In this text, Lynne Parenti and Malte Ebach address this discord and outline comparative tools to unify biogeography. Rooted in phylogenetic systematics, this comparative biogeographic approach offers a comprehensive empirical framework for discovering and deciphering the patterns and processes of the distribution of life on Earth. The authors cover biogeography from its fundamental ideas to the most effective ways to implement them. Real-life examples illustrate concepts and problems, including the first comparative biogeographical analysis of the Indo-West Pacific, an introduction to biogeographical concepts rooted in the earth sciences, and the integration of phylogeny, evolution and earth history.
New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p