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The burden of neurodegenerative disorders has been increasing as a consequence of a growing elderly population. These multifactorial diseases do not have a cure or efficient treatments. Due to its mechanistic complexity, prevention and treatment will require novel multi-targeted therapeutic strategies, targeting different disease hallmarks. The possibility of altering the progression and development of diseases through diet is an emerging as attractive approach with increasing supporting data. Epidemiological and clinical studies have highlighted the health potential of diets rich in fruits and vegetables. Studies with dietary (poly)phenols have been showing their multipotent and pleiotropic...
Health care demands more and more cooperation and the convergence of all health related sciences, from Life Molecules to Global Health, as was most recently shown by the challenge of the COVID pandemic. This book brings together science contributions from NOVA’s researchers on biology and health, in the format of a broad life construct book.
Presents recent research on metabolism and the health effects of polyphenols Consumer interest in the health benefits of many phenolic compounds found in plant foods and derivatives has grown considerably in recent years, giving rise to an increased demand for functional foods. Although preclinical and observational studies have promoted the protective properties of polyphenols for a range of chronic diseases, evidence has shown that most dietary polyphenols have little bioavailability. Once ingested, most of them are metabolized by either the intestinal enzymes or by the gut microbiota and then undergo extensive phase-II metabolism reaching significant concentrations of conjugated metabolit...
This comprehensive book brings together international experts to review state-of-the-art research findings on the exponentially growing area of berries and berry bioactive compounds in promoting health.
Plant polyphenols are specialized metabolites that constitute one of the most common and widespread groups of natural products. They are essential plant components for adaptation to the environment and possess a large and diverse range of biological functions that provide many benefits to both plants and humans. Polyphenols, from their structurally simplest forms to their oligo/polymeric versions (i.e. tannins and lignins), are phytoestrogens, plant pigments, antioxidants, and structural components of the plant cell wall. The interactions between tannins and proteins are involved in plant defense against predation, cause astringency in foods and beverages, and affect the nutritional and heal...
"Em Busca do Tempo Perdido", a obra monumental de Marcel Proust, é descrita como uma experiência literária que transcende a simples leitura, exigindo do leitor uma dedicação intensa e prolongada. Frequentemente citada, mas raramente lida em sua totalidade, a obra é cercada de lendas que ofuscam a experiência real de sua leitura. Em 2021, Marcus Alexandre Motta propôs a formação de um grupo de leitura para explorar e discutir a obra, reunindo alunos novos e antigos em encontros semanais on-line. Esse grupo, livre das pressões acadêmicas, dedicou-se à leitura meticulosa e à reflexão crítica da obra. Além da leitura, o grupo produziu fragmentos chamados "cacos", que buscaram dialogar com Proust e entre si, culminando em uma coleção que reflete a natureza complexa e múltipla da obra original. As contribuições também incluíram composições visuais, enriquecendo a interpretação coletiva dos trabalhos. O resultado é um livro que, assim como "Em Busca do Tempo Perdido", é um mosaico de experiências temporais e reflexões que convida o leitor a uma imersão profunda e paciente no universo proustiano.
This book is a compilation of some of the most remarkable contributions made by scientists currently working in Latin America to the understanding of virus biology, the pathogenesis of virus-related diseases, virus epidemiology, vaccine trials and antivirals development. In addition to recognizing the many fine virologists working in Latin America, Human Virology in Latin America also discusses both the state-of-the-art research and the current challenges that are being faced in the region, in hopes of inspiring young scientists worldwide to become eminent virologists.
Este livro é o resultado dos estímulos dos professores da disciplina Integração Prática Clínica I (IPC-I), investidos no propósito de estimular a produção científica dos estudantes do 5º período do Curso de Medicina da Faculdade Metropolitana São Carlos-FAMESC, Unidade de Bom Jesus do Itabapoana-RJ, turmas 2021-1 e 2021-2. A obra explora de forma objetiva os principais agravos presentes na prática clínica.
Este livro é o resultado dos estímulos dos professores da disciplina Integração Prática Clínica I (IPC-I), investidos no propósito de estimular a produção científica dos estudantes do 5º período do Curso de Medicina da Faculdade Metropolitana São Carlos-FAMESC, Unidade de Bom Jesus do Itabapoana-RJ, turmas 2021-1 e 2021-2. A obra explora de forma objetiva os principais agravos presentes na prática clínica.