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Beyond All Things
Beyond All Things takes the reader on a spiritual journey through the physical, intellectual, and emotional aspects of being.Throughout this unique work, the insights and questions for contemplation beckon the reader to welcoming more light, uplifting inspiration, and feelings of connectivity into daily living. The reader quickly discovers, by reading and implementation, that even small changes in perspective have tremendous power to change our lives, and in turn... the world.In contemplating That which is Beyond All Things and learning to channel our highest selves through mindful thought, speech, and practical action, we begin to align with joy, purpose, and a personal, one-of-a-kind spiri...
It's Not a Man's World
It's Not A Man's World: How I conquered the sins of my father paints a vivid picture of what life is like for a male growing up in a fatherless household. It's the reflective process of one man's journey to heal himself from his father's rejection. It's a story of love, loss, and insecurities as L.T. fights to become a man in a world that sometimes seemed intent on making him fail. As he reflects on his path and invites readers into his world, he squashes the notion of the 'macho man' persona by exposing the truth that there are males who are silently fighting through some of life's most difficult challenges. L.T. encourages these males to become more vocal about their childhood experiences and vulnerabilities, as it is the only way they will be liberated from their pain.As L.T. learns the importance of conquering his father's sins, he realizes that it's not a man's world after all.
Muscle Atrophy
The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thi...
Timetables of World Literature
Which authors were contemporaries of Charles Dickens? Which books, plays, and poems were published during World War II? Who won the Pulitzer Prize in the year you were born? Timetables of World Literature is a chronicle of literature from ancient times through the 20th century. It answers the question "Who wrote what when?" and allows readers to place authors and their works in the context of their times. A chronology of the best in global writing, this valuable resource lists more than 12,000 titles and 9,800 authors, includes all genres of literature from more than 58 countries, and covers 41 languages. It is divided into seven sections, spanning the Classical Age (to 100 CE), the Middle A...
Rating Scales in Parkinson's Disease
For many years, the need to develop valid tools to evaluate signs and symptoms of Parkinson Disease (PD) has been present. However the understanding of all intricacies of rating scales development was not widely available and the first attempts were relatively crude. In 2002, the Movement Disorders Society created a task force to systemize the measurement of Parkinson's Disease. Since then, the Task Force has produced and published several critiques to the available rating scales addressing both motor and non-motor domains of Parkinson Disease. Additionally the task force initiated a project to develop a new version of the UPDRS, the MDS-UPDRS. But none of this was made available in one conv...
Exon Skipping and Inclusion Therapies
This book presents a comprehensive collection of detailed state-of-the-art exon skipping and splices modulation protocols. Chapters detail 14 genetic diseases, AON-mediated therapies, and CRISPR/Cas9-mediated gene editing therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Exon Skipping and Inclusion Therapies: Methods and Protocols aims to help researchers initiate the development of next-generation therapies.
Functional Proteomics
As the emerging field of proteomics continues to expand at an extremely rapid rate, the relative quantification of proteins, targeted by their function, becomes its greatest challenge. Complex analytical strategies have been designed that allow comparative analysis of large proteomes, as well as in depth detection of the core proteome or the interaction network of a given protein of interest. In Functional Proteomics: Methods and Protocols, expert researchers describe the latest protocols being developed to address the problems encountered in high-throughput proteomics projects, with emphasis on the factors governing the technical choices for given applications. The case studies within the v...
The Law of Outer Space
It is a remarkable achievement to write a book that almost four decades after its publication has lost virtually none of its relevance. Manfred Lachs’ famous treatise on the Law of Outer Space was originally published in 1972, yet it is still a classic and must-read text for space law students today, even though copies can nowadays be rarely found. The reissue of this remarkable work is therefore timely indeed. Its aim is to make the brilliance, foresight and clarity of Lachs’ thinking once more easily accessible to a new generation of scholars. Issued on the occasion of the 50th anniversary of the International Institute of Space Law, of which Lachs was President, this volume reproduces the original text of Lachs' work in full, with a new preface, introduction and index supplied by the editors.
The Futurist Files
Futurism was Russia's first avant-garde movement. Gatecrashing the Russian public sphere in the early twentieth century, the movement called for the destruction of everything old, so that the past could not hinder the creation of a new, modern society. Over the next two decades, the protagonists of Russian Futurism pursued their goal of modernizing human experience through radical art. The success of this mission has long been the subject of scholarly debate. Critics have often characterized Russian Futurism as an expression of utopian daydreaming by young artists who were unrealistic in their visions of Soviet society and naïve in their comprehension of the Bolshevik political agenda. By t...
Town Hall, Säynätsalo
Aalto's Town Hall at Saynatsalo embodies his concern for buildings as intermediaries between human life and the landscape. Acting as a focal point in the town, it is approached by a forest path and a series of steps.
