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Iniciativas para la sustentabilidad. Transformando personas, construyendo país
En esta obra se reúnen las iniciativas, pero también las experiencias vividas, por las y los autores que han participado como estudiantes de distintas promociones de las siete primeras versiones del Diplomado en Educación para el Desarrollo Sustentable y cómo este, tanto en la interacción del ejercicio académico de intercambio de saberes como la experiencia –en sí misma– de haberlo cursado ha significado en su desarrollo como persona y en la ejecución de su iniciativa en el colectivo al que pertenece. Consideramos, entonces, que el mayor mérito de este libro es presentar la huella que ha dejado en las y los autores de las iniciativas este diplomado surgido en una época de movilizaciones sociales por una educación gratuita y de calidad que ha marcado a la sociedad chilena.
Holy Terrors
DIVTranslations of texts by important Latin American women playwrights, and performance artists, together with essays about their work./div
ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins
With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. • Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs • Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective • Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines • Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan • Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain
¡Basta! + de 100 Mujeres contra la violencia de género
La conocida escritora Virginia Vidal, señala: -“De esta creación femenina resultan verdaderas joyas destinadas a permanecer en el tiempo. Cien formas de asomarse a una realidad palpable y atroz que nuestro país necesita asumir, constituyen un paisaje poblado de historias que sublevan, entristecen, imponen una reflexión”. En la segunda edición junto a a los cuentos de Alejandra Costmagna, Andrea Jeftanovic o Lina Meruane, se compilan los textos de Carmen Berenguer, Larissa Contreras, Soledad Fariña, Nona Fernández y Eugenia Prado, entre otras, las que aceptaron el reto de escribir un mini relato acerca de la violencia de género en no más de 150 palabras. Esta iniciativa se ha replicado en numerosos países con escritores de cada nación. También en USA en “Cien Latinas contra la violencia de género” a cargo de la escritora Ema Sepúlveda, entre otros. En 2014 se publicó la versión bilingüe traducida por Martha Manier, profesora emérita de la Humbolt State University (CA), con la colaboración de la profesora Jacqueline Nanfito.
Notes on Puerto Rican Revolution
This essay on Puerto Rico analyzes the deepening crisis in American capitalism and how it inevitably affects Puerto Rico. Essentially, Lewis asks and seeks to answer three questions: What is the nature of Puerto Rican society after a decade of dramatic and traumatic change? What should be the strategy of freedom? What can be, ought to be, the nature of the new Puerto Rican society, once it is released from American rule?
Cannabinoid Modulation of Emotion, Memory, and Motivation
The endocannabinoid system consists of cannabinoid receptors, their endogenous lipid ligands (endocannabinoids) and the enzymatic machinery for their synthesis and degradation. In the brain, endocannabinoids regulate ion channel activity and neurotransmitter release and thereby contribute to various aspects of brain function, including memory, reward and emotions. Their ability to modulate synaptic efficacy has a wide range of functional consequences and provides unique therapeutic possibilities. Unprecedented advances have been made in the understanding of the role of endocannabinoids in the regulation of the emotional brain over the past few years. However, a comprehensive book encompassing all these aspects is still lacking. The book will provide an overview of the role played by the endocannabinoid system in the regulation of emotional processes with particular emphasis on the modulation of memory and reward for emotionally arousing events and for the regulation of motivational aspects in cannabis use.
Neuropeptide GPCRs in neuroendocrinology
The human genome encompasses ˜ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. GPCRs are also major drug targets and hence possess a strong potential for the development of innovative pharmaceuticals. The aim of this Research Topic was to assemble a series of review articles and original research papers on neuropeptide GPCRs and their ligands that would illustrate the different facets of the studies currently conducted in this domain.
Food Packaging
Food Packaging: Innovations and Shelf-life covers recently investigated developments in food packaging and their influence in food quality preservation, shelf-life extension, and simulation techniques. Additionally, the book discusses the environmental impact and sustainable solutions of food packaging. This book is divided into seven chapters, written by worldwide experts. The book is an ideal reference source for university students, food engineers and researchers from R&D laboratories working in the area of food science and technology. Professionals from institutions related to food packaging.
Science and Technology for the Conservation of Cultural Heritage
From 2nd to 5th October 2012 an International Congress on Science and Technology for the conservation of Cultural Heritage was held in Santiago de Compostela, Spain, organized by the Universidade of Santiago de Compostela on behalf of TechnoHeritage Network. The congress was attended by some 160 participants from 10 countries, which presented a total of 145 contributions among plenary lectures, oral, and poster communications. The congress was dedicated to eight topics, namely (1) Environmental assessment and monitoring (pollution, climate change, natural events, etc.) of Cultural Heritage; (2) Agents and mechanisms of deterioration of Cultural Heritage (physical, chemical, biological), incl...
