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Checklist of Helminth Parasites of Amphibians from South America
Parasitological studies on helminths of amphibians in South America have increased in the past few years. Here, we present a list with summarized data published on helminths of South American amphibians from 1925 to 2012, including a list of helminth parasites, host species, and geographic records. We found 194 reports of helminths parasitizing 185 amphibian species from eleven countries: Argentina, Brazil, Chile, Colombia, Equador, French Guyana, Guyana, Paraguay, Peru, Uruguay and Venezuela. Helminth biodiversity includes 278 parasite species of the groups Acanthocephala, Nematoda, Cestoda, Monogenea and Trematoda. A list of helminth parasite species per host, and references are also presented. This contribution aims to document the biodiversity of helminth parasites in South American amphibians, as well as identify gaps in our knowledge, which in turn may guide subsequent studies.
Antiviral Drug Discovery and Development
This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced clinical development. Special attention is paid to viral infections with a high impact on the world population or highly relevant from the public health perspective (HIV, hepatitis C, influenza virus, etc.). In these chapters, limitations associated with adverse effects and emergence of drug resistance are discussed in detail. In addition to classical antiviral strategies, chapters will be dedicated to discuss the non-classical drug development strategies to block vira...
EDUCAÇÃO, SOCIEDADE E MEIO AMBIENTE: desafios, saberes e práticas
A aglutinação de questões envolvendo Educação, Sociedade e Meio Ambiente torna-se cada vez mais necessária em um contexto de ressignificação das nossas ações. Esta obra traz em sua essência mobilizações, temáticas e problematizações que abrangem diferentes sentidos e contextos, fortalecendo ainda mais as demandas para outra sustentabilidade.
Advances in Bioinformatics and Computational Biology
This book constitutes the proceedings of the 15th Brazilian Symposium on Bioinformatics on Advances in Bioinformatics and Computational Biology, BSB 2022, which took place in Buzios, Brazil, in September 2022. The 10 full papers and 7 short papers presented in this volume were carefully reviewed and selected from 23 submissions. The papers focus on bioinformatics, computational biology, Biological Databases, Biological Networks, Cheminformatics, Evolutionary Genomics, Computational Proteomics, Systems Biology, Drug Design, Genomics, Machine Learning applications in Bioinformatics, Metagenomics, Molecular Docking and Modeling, Molecular Evolution and Phylogenetics, Protein Structure and Modeling, Proteomics, Transcriptomics, Single-Cell Analysis, Workflows in Bioinformatics.
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Forest Cover Change in Space and Time
This paper presents a framework for analyzing tropical deforestation and reforestation using the von Thunen model as its starting point: land is allocated to the use which yields the highest rent, and the rents of various land uses are determined by location. Forest cover change therefore becomes a question of changes in rent of forest versus non-forest use. While this is a simple and powerful starting point, more intriguing issues arise when this is applied to analyze real cases. An initial shift in the rent of one particular land use generates feedbacks which affect the rent of all land uses. For example, a new technology in extensive agriculture should make this land use more profitable a...
Computational Biomechanics
The combination of readily available computing power and progress in numerical techniques has made nonlinear systems - the kind that only a few years ago were ignored as too complex - open to analysis for the first time. Now realistic models of living systems incorporating the nonlinear variation and anisotropic nature of physical properties can be solved numerically on modern computers to give realistically usable results. This has opened up new and exciting possibilities for the fusing of ideas from physiology and engineering in the burgeoning new field that is biomechanics. Computational Biomechanics presents pioneering work focusing on the areas of orthopedic and circulatory mechanics, using experimental results to confirm or improve the relevant mathematical models and parameters. Together with two companion volumes, Biomechanics: Functional Adaptation and Remodeling and the Data Book on Mechanical Properties of Living Cells, Tissues, and Organs, this monograph will prove invaluable to those working in fields ranging from medical science and clinical medicine to biomedical engineering and applied mechanics.
Manual do Paciente com Câncer
Segundo a Organização Mundial da Saúde (OMS), o câncer está entre as dez doenças que mais ceifam vidas no mundo. Há séculos, a medicina vem lutando contra essa doença, que segundo o médico oncologista Siddhartha Mukherjee cita em seu livro O Imperador de Todos Os Males - uma biografia do câncer: "Se nós, como espécie, somos o produto final da seleção darwiniana, essa doença impressionante que espreita dentro de nós também é". Essa patologia vem desafiando a humanidade desde o florescimento das civilizações. Mas afinal o que é o câncer? Como tratar? Quais são as perspectivas de cura? Quais são os direitos dos pacientes oncológicos? Essas e outras perguntas importante...
