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Pharmacogenomics and Personalized Medicine
Pharmacogenomics is one of the emerging approaches to precision medicine, tailoring drug selection and dosing to the patient’s genetic features. In recent years, several pharmacogenetic guidelines have been published by international scientific consortia, but the uptake in clinical practice is still poor. Many coordinated international efforts are ongoing in order to overcome the existing barriers to pharmacogenomic implementation. On the other hand, existing validated pharmacogenomic markers can explain only a minor part of the observed clinical variability in the therapeutic outcome. New investigational approaches are warranted, including a study of the pharmacogenomic role of the immune...
Evidence-based Management of Lipid Disorders
Practising evidence-based medicine necessarily depends on the clinician having access to the best evidence available, but in a fast-moving field, keeping up to date with the latest developments is a challenging prospect. In this new volume, leading experts focus on the most important clinical issues associated with the management of lipid disorders, evaluating and interpreting the evidence available to provide the reader with a reliable summary of our current knowledge. Topics covered include therapeutical strategies for managing hereditary lipid disorders, including familial hypercholesterolemia, both in adults and children, and familial combined hypercholesterolemia. The authors also evalu...
Regional Cancer Therapy
This volume provides a biological and pharmacological background for regional cancer therapy, strategies and techniques for regional therapies, and specific indications and results for different tumor entities. Clinical trial concepts and detailed treatment protocols are also presented. This book is essential reading for researchers and clinicians engaged in seeking advanced therapeutic options for cancer patients worldwide.
Bioinformatics and Beyond
This book is a comprehensive exploration of the dynamic interplay between bioinformatics and artificial intelligence (AI) within the healthcare landscape. This book introduces readers to the foundational principles of bioinformatics and AI, elucidating their integration and collaborative potential. Bioinformatics and Beyond: AI Applications in Healthcare explores the transformative impact of data-driven insights, showcasing the applications of machine learning in diagnostics, personalized medicine, and genomic advancements. The book unveils the pivotal role AI plays in accelerating pharmaceutical research. Moreover, it addresses the practical implementation of AI in clinical decision support...
Medical English as a Lingua Franca
In this first book-length treatment of MELF, the authors assert that MELF represents an important contribution to our understanding of English as a Lingua Franca (ELF), in that existing ELF research has been limited to relatively low stakes communicative situations, such as interactions in business, academia, internet blogging or casual conversations. Medical contexts, in contrast, often represent situations calling for exceptional communicative precision and urgency. Providing both evidence from their own research and analysis from (the limited number of) existing studies, the authors offer a counterpoint to the optimism regarding communicative success prevalent in ELF. The book proposes a theoretical perspective on how the various features of healthcare communication serve as important variables in shaping interaction among speakers of ELF, further enlarging our understanding of this emerging sub-field.
Current Topics in Molecular Diagnostics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine, E-Book
In this issue of Clinics in Laboratory Medicine, guest editor Dr. Gregory Tsongalis brings his considerable expertise to Current Topics in Molecular Diagnostics and Precision Medicine. Top experts in the field cover key topics such as syndromic and point-of-care molecular testing; building evidence for clinical use of pharmacogenomics and reimbursement for testing; precision medicine using pharmacogenomic panel-testing; and more. - Contains 12 relevant, practice-oriented topics including next-generation sequencing approaches to predicting antimicrobial susceptibility testing results; the role of the human gutome on chronic disease: a review of the microbiome and nutrigenomics; blood group ge...
