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A incidência do Imposto Territorial Rural de acordo com a sustentabilidade e finalidade socioeconômica da atividade empresarial rural
O presente estudo tem como foco abordar o Imposto Territorial Rural (ITR), dando ênfase a uma análise a respeito do critério utilizado para observar a incidência do ITR a partir da finalidade econômica do imóvel. É sabido que os arts. 29 e 32 do Código Tributário Nacional não fornecem critérios objetivos para a delimitação da hipótese de incidência tributária do IPTU e do ITR. Desse modo, o critério da destinação, lastreado no art. 15 do Decreto-Lei n° 57 de 1966, este recepcionado pela Constituição Federal com status de lei complementar, surge como pacificador dessa controvérsia. Ocorre que, diante de um cenário de crescimento desordenado das cidades e de situações...
Building a Life of Value
How Do Your Build a Meaningful Life? More than just a book of quotations, this book is a fusion of great thinking from classical to contemporary, from philosophical to poetic. It is a concert of voices, harmoniously blended by Jason Merchey and his thought-provoking essays. It will stimulate your thinking, energize your spirit, and deepen your understanding of human nature. It presents progressive ideals at their best - humane, humanistic, and high-minded. Consider it your shaman, your oracle, your foundation, your blueprint for truly building a life of value. With these ideas we can improve ourselves, our planet, and our future.
Bone Marrow Niche
This volume summarizes recent advances in research on mesenchymal cell populations in the bone marrow. It explores how mesenchymal cells create niches for immune cells in extramedullary organs and it discusses new concepts of lympho-hematopoietic microenvironments. Readers are introduced to the fundamentals of hematopoietic stem cells (HSCs) differentiation to all types of blood cells, including immune cells, in the bone marrow. The book highlights how this process is supported and regulated by the individual microenvironments of stem cells, termed niches. The identity of HSC niches has been subject to longstanding debates. Recent studies identified the population of mesenchymal stem cells as the major cellular component of niches, for hematopoietic stem and progenitor cells (HSPCs) and their candidate developmental origin. Furthermore, candidate cellular niches for immune cells in lymph nodes and adipose and connective tissues were identified. The authors of this volume focus on shared features between those and HSPC niche cells in the bone marrow. Covering latest research results, this book serves as fascinating read for researchers and clinicians in hematology and immunology.
Brain Morphometry
This volume presents the latest methods and approaches used to better characterize the properties of the structural human brain, and also explores various dysfunctional and non-dysfunctional neuroanatomical variations. This book is divided into 3 parts: methods, non-clinical applications, and clinical applications. The chapters in Part 1 talk about methods to study cortical thickness and the general linear model. Part 2 covers changes in brain structure from birth to adulthood, and morphometry of the corpus callosum. Part 3 discusses applications to study Alzheimer’s Disease, Parkinson’s Disease, epilepsy, Schizophrenia, and suicide. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Brain Morphometry is a valuable resource for students, clinicians, and researchers who are interested in this developing field.
Active Materials
What are active materials? This book aims to introduce and redefine conceptions of matter by considering materials as entities that ‘sense’ and respond to their environment. By examining the modeling of, the experiments on, and the construction of these materials, and by developing a theory of their structure, their collective activity, and their functionality, this volume identifies and develops a novel scientific approach to active materials. Moreover, essays on the history and philosophy of metallurgy, chemistry, biology, and materials science provide these various approaches to active materials with a historical and cultural context. The interviews with experts from the natural scien...
Chronic Liver Failure
Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
Diagnostics, Risk Factors, Treatment and Outcomes of Acute Kidney Injury in a New Paradigm
Acute kidney injury (AKI) is a frequent clinical syndrome among hospitalized patients, independently associated with both short- and long-term mortality. Previous investigations attempted to identify effective interventions to prevent AKI or promote kidney function recovery in patients with AKI. Most were unsuccessful. Hence, additional studies are required in the field of AKI research. In this Special Issue, we are making a call to action to stimulate researchers and clinicians to submit their studies on AKI conducted in nephrology, internal medicine, critical care, and other disciplines that will provide additional knowledge and skills in the field of AKI research, ultimately to improve patient outcomes.
Marginal Donors
In response to persistent donor organ shortages, organs from marginal donors, such as expanded criteria donors (ECD) and donation after cardiac death (DCD) donors, are now accepted and have been successfully transplanted, reducing the waiting times for transplantation. Especially in Japan, transplantation of DCD kidneys has a relatively long history because of the difficulty or lack of national consensus in accepting brain death, which has made it possible to accumulate considerable clinical experience. Thus, the current organ shortage has stimulated interest in the use of marginal donors for transplantation. On the other hand, however, it is known that these organs have a high rate of delay...
Biomaterial-Related Infections
The use of medical devices (e.g., catheters, implants, and probes) is a common and essential part of medical care for both diagnostic and therapeutic purposes. However, these devices quite frequently lead to the incidence of infections due to the colonization of their abiotic surfaces by biofilm-growing microorganisms, which are progressively resistant to antimicrobial therapies. Several methods based on anti-infective biomaterials that repel microbes have been developed to combat device-related infections. Among these strategies, surface coating with antibiotics (e.g., beta-lactams), natural compounds (e.g., polyphenols), or inorganic elements (e.g., silver and copper nanoparticles) has bee...
Critical by Design?
In its constructive and speculative nature, design has the critical potential to reshape prevalent socio-material realities. At the same time, design is inevitably normative, if not often violent, as it stabilises the past, normalises the present, and precludes just and sustainable futures. The contributions rethink concepts of critique that influence the field of design, question inherent blind spots of the discipline, and expand understandings of what critical design practices could be. With contributions from design theory, practice and education, art theory, philosophy, and informatics, »Critical by Design?« aims to question and unpack the ambivalent tensions between design and critique.
