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Regional Anatomy
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The Merkel Cell
Since their first description in 1875, Merkel cells have remained an elusive cell type. Their origin as well as their classification as mechanoreceptors have been a matter of controversy and intense discussion. The peptidergic granules in these cells are suggestive of neuroendocrine functions, but their discovery has raised additional questions regarding Merkel cell function. Essential aspects of structure, development and function of normal Merkel cells and Merkel cell carcinoma are presented in short chapters, providing concise and up-to date information on this fascinating cell type.
Hands of Primates
The hand commonly is considered to have exerted great influence on the evolution of typically human characteristics, like upright posture, stereoscopic vision, «manipulative» handling of parts of the environment. The German term «Begreifen», which is commonly used for the understanding of complex relationships in a generalised, abstract sense, always implies the original meaning of seizing objects with the aid of the hands. The hands are also of greatest importance for the survival of the other, non-human primates. Hands are absolutely essential for locomotion in an arboreal habitat, and the intake of food is dependant on the use of the hands as well: primates very rarely take in food di...
The Origin and Fate of Somites
This text investigates advances in the field of sommites and integrates them into the accumulated knowledge of how sommites form and differentiate. Although the book focuses on the formation and patterning of somites it will encompass a broader life history of a somite. Topics include events attending gastrulation, which foreshadow somite formation, to the subsequent contributions that somites make to neighbouring regions such as musculature, limbs and axial skeleton. There is also a discussion of the origins of cells that eventually give rise to somites. This book brings together investigators from NATO and NATO partner countries who are employing both classical and molecular approaches to the analysis of somitogenesis.
Developmental Patterning of the Vertebrate Limb
Following pioneering work by Harrison on amphibian limbs in the 1920s and by Saunders (1948) on the apical ridge in chick limbs, limb development became a classical model system for investigating such fundamental developmental issues as tissue interactions and induction, and the control of pattern formation. Earlier international conferences, at Grenoble 1972, Glasgow 1976,and Storrs, Connecticut 1982, reflected the interests and technology of their time. Grenoble was concerned with ectoderm-mesenchyme interaction, but by the time of the Glasgow meeting, the zone of polarizing activity (ZPA) and its role in control of patterning was the dominant theme. Storrs produced the first intimations t...
Formation and Differentiation of Early Embryonic Mesoderm
Mesodenn is a key tissue in early development. It is involved in the differentiation of almost every organ in the body, not merely as a structural component, but as an active participant in the establishment of diverse cell types. All mesodenn is derived from ectoderm. Its appearance signals the start of a significant new phase in the development of the embryo. At this time all three genn layers are now present and myriad sequences of cell and tissue interactions begin to occur which will eventually give rise to the entire embryo. The control of the growth and differentiation of the mesoderm is critical for the production of a normal individual. Indeed, disturbance of the patterning of the m...
Anatomie
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Batting on the Bosphorus
Angus Bell is innocently working in the Montreal magazine industry when, taking advantage of a psychic's vision, he sets off to discover the secret cricketing world of Eastern Europe. From tournaments on ice in Estonia to university leagues in the crumbling Crimea, and from a Croatian military island to communist Belarus, Bell learns how Slavs play the Englishman's game. Encounters with fingerless Tamil Tigers in Prague, a bomb-plotter in the Austrian Alps, a Guatemalan anarchist, and an MI6 agent making out lineup cards reveal the shadowy side of Slavic cricket. But nothing can stop Bell from playing the game or even becoming the captain of an international team. Between matches, he's pursued by the KGB, becomes embroiled in a drug bust on the Midnight Express, and needs emergency treatment from a Romanian dentist. This boisterous traveler's tale redefines the spirit of cricket, converting even sworn enemies of the game into avid fans.
Limb Development and Regeneration
This volume (in two parts) appears at a pivotal time for the study of pattern formation. The data from decades of experimental manipulation of the limb are now being used to help gain perspective and understanding on the explosion of descriptive information on the molecular biology of amniote development. These proceedings of the Fourth International Conference on Limb Development and Regeneration, held in Asilomar, California, July 1992, comprise 81 papers on such topics as the role of Hox genes in limb development; expression of homeobox genes in limb regeneration; why does a limb look like a limb?; lessons from extra digits, analysis of the mutant axolotl short toes; endothelial cell differentiation in the chick limb; in vitro mammalian limb differentiation as an experimental model; and retinoic acid and limb pattern formation. Parts A and B are not sold separately. Annotation c. by Book News, Inc., Portland, Or.
Batting In The Baltic
Scotsman Angus Bell is minding his own business in Montreal when a psychic tells him he'll be leaving North America to embark on a travelling media project. When the words 'cricket' and 'Ukraine' pop into his head, he sets off to fulfil his destiny. A voyage of surprising discovery is in store for him: not only do they play cricket right across central and eastern Europe, bu they're as passionate about the game as he is. From tournaments on ice in Estonia to university leages in the crumbling Crimea, from a Croatian military island to communist Belarus, Slavs are playing the Englishman's game. Angus uncovers a shadowy side of eastern European cricket too; with fingerless 'Tamil Tigers' in Pr...
