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Published Scientific Papers of the National Institutes of Health
Presents the broad outline of NIH organizational structure, theprofessional staff, and their scientific and technical publications covering work done at NIH.
Molecular Biology of Neuropsychiatric Disorders
It is generally accepted that neuropsychiatric disorders have a biological basis. Pathological changes leading to illness have been confirmed for Alzheimer’s (amyloid plaques) and Parkinson’s disease (loss of dopaminergic transmission) and are the foundation for studies on the molecular biology of these disorders. For other neuropsychiatric disorders, in particular for schizophrenic and affective disorders, molecular causes appear to be more complex and therefore remain hypothetical, despite decades of research. Changes in a number of neuronal pathways and structures have been reported to be associated with these disorders and are currently under extensive investigation. The present volume reviews recent knowledge with emphasis on ongoing research findings. Current hypotheses based on these findings are described and discussed.
Genetic Approaches to Mental Disorders
Since the 1940s, the American Psychopathological Association has been a driving force in psychiatric genetic research. Having studied the Kallmann and Kety Hoch Award papers, many researchers have attempted to advance psychiatric genetic knowledge from epidemiological findings to biological findings. Genetic Approaches to Mental Disorders provides the latest information on the relationship between genetics and mental disorders. Divided into four sections, this book presents analysis of the genetic data, linkage mapping and association, debate over genetic Kraepelinian dichotomy, and mapping and association results in psychiatry.
The Genetic Basis of Common Diseases
Since the first edition of this highly acclaimed text was published in 1992, much new knowledge has been gained about the role of genetic factors in common adult diseases, and we now have a better understanding of the molecular processes involved in genetic susceptibility and diseases mechanisms. The second edition fully incorporates these advances. The entire book has been updated and twelve new chapters have been added. Most of these chapters deal with diseases such as gallstones, osteoporosis, osteoarthritis, skin cancer, other common skin diseases, prostate cancer and migraine headaches that are seen by all physicians. Others address the genetic and molecular basis of spondylarthropathies, lupus, hemochromatosis, IgA deficiency, mental retardation, hearing loss, and the role of mitochondrial variation in adult diseases. Chapters on the evolution of human genetic disease and on animal models add important background on the omplexities of these diseases. Unique clinical applications of genetics to common diseases are covered in the additional new chapters on genetic counseling, pharmacogenetics, and the genetic consequences of modern therapeutics.
Childhood Onset of 'Adult' Psychopathology
Age at onset studies have been an important approach to understanding disease across all medical specialties. Over the last few decades, genetic research has led to the identification of unique genes and, in some cases, physiologically different disorders. These advances bring us closer to identifying genetic vulnerability and implementing prevention programs for psychopathology. Childhood Onset of "Adult" Psychopathology: Clinical and Research Advances provides an understanding of the childhood onsets of adult psychiatric disorders, including when and in what sequence psychiatric disorders begin in childhood, and how these disorders evolve over the life span. This book examines Studies on t...
Psychiatric Genetics
Psychiatrists and other mental health professionals are increasingly confronted with questions about the genetics of psychiatric illness, and the clinical applications of new genetic findings. Psychiatric Genetics: A Primer for Clinical and Basic Scientists addresses these questions through a straightforward introduction to the essentials of psychiatric genetics, complementing more comprehensive textbooks that may seem overwhelming for those new to the field. Written and edited by leaders in the field and the International Society of Psychiatric Genetics (ISPG), the book covers basic epidemiology, recruitment for human studies, phenotyping strategies, formal genetic and molecular genetic stu...
Mental Disability Law, Evidence, and Testimony
This new book written by ABA Commission on Mental and Physical Disability Law Director, John Parry, J.D. and forensic psychologist, Eric Y. Drogin, J.D., Ph.D., Manual has been formatted and written to guide lawyers, judges, law students, and forensic and other mental disability professionals through the maze of civil and criminal laws, standards, and evidentiary pitfalls, and forensic practices that characterize this area of the law. Moreover, it summarizes what empirical evidence exists to support or raise concerns about these legal standards and forensic practices when they are introduced in the courtroom.
On Behalf of God
"A comprehensive and useful discussion of Christian ethics applied to a variety of difficult and timely issues is no simple task, but Reichenbach and Anderson have risen to it. They have provided a book that is a great starting place for further consideration of topics such as the environment, assisted reproduction, abortion, surrogacy, the human genome, the pursuit of knowledge, the brain-mind issue, and human sexuality. Their treatment of these issues is integrated by the adoption of a biblically based paradigm from Genesis: 'filling, ' 'ruling over, ' and 'caring for.' This is a book packed with information, suggestions, and challenges." -Richard Bube, Stanford University "An important bo...
