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Different Phenotypes of Drug-induced Anaphylaxis - Data from the European Anaphylaxis Registry
Abstract: Background Drugs are a frequent cause of severe anaphylactic reactions. Here, we analyze a large dataset on drug induced anaphylaxis regarding elicitors, risk factors, symptoms, and treatment. Methods Data from the European Anaphylaxis Registry (2007-2019) with 1815 reported cases of drug-induced anaphylaxis were studied accordingly. Results Drugs are the third most frequent cause of anaphylaxis reported in the Anaphylaxis Registry. Among the eliciting groups of drugs analgesics and antibiotics were far most often reported. Female and senior patients were more frequently affected, while the number of children with DIA was low. DIA patients had symptoms affecting the skin and mucous...
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The Importance of Pharmacovigilance
The purpose of this document is to present the case for the importance of pharmacovigilance, to record its growth and potential as a significant discipline within medical science, and to describe its impact on patient welfare and public health.
Sędzia
Dziennikarz Kuba Zimny pisze artykuł o Adamie Bonarze, właścicielu świetnie prosperującej firmy leasingowej, nagle pomówionym o oszukanie inwestorów na sumę 300 mln złotych. Bonar rozumie, że padł ofiarą manipulacji zmierzających do przejęcia jego firmy, i rozpoczyna niebezpieczną akcję odwetową, w której będzie się musiał zmierzyć z dwoma bardzo silnymi przeciwnikami: Księżnym, byłym funkcjonariuszem SB, a obecnie prezesem banku, i bezwzględnym sędzią Foglem. Bonara czeka wiele kłopotów, a czytelnika – lawina dramatycznych zdarzeń, z dwoma morderstwami włącznie. „Sędzia” to trzymający w napięciu thriller prawniczy, demaskujący powiązania między politykami, finansistami i cynicznymi prawnikami, którzy zapewniają przestępcom niekaralność i swobodę działania. Mariusz Zielke kolejny raz zdziera obnaża prawdziwe oblicze świata finansjery i kreśli prawdziwe oblicze świata, w którym prawo jest dla bogatych, a nie dla biednych.
Advances in Databases and Information Systems
This volume is the second one of the 16th East-European Conference on Advances in Databases and Information Systems (ADBIS 2012), held on September 18-21, 2012, in Poznań, Poland. The first one has been published in the LNCS series. This volume includes 27 research contributions, selected out of 90. The contributions cover a wide spectrum of topics in the database and information systems field, including: database foundation and theory, data modeling and database design, business process modeling, query optimization in relational and object databases, materialized view selection algorithms, index data structures, distributed systems, system and data integration, semi-structured data and dat...
McRae's Orthopaedic Trauma and Emergency Fracture Management
This book is derived from Ronald McRae’s Pocketbook of Orthopaedics and Fractures, a highly successful ‘survival guide’ for the trainee working in accident and emergency or orthopaedic departments. Retaining the underlying principles of the original editions this comprehensive rewrite and re-presentation provides complete coverage of orthopaedic trauma surgery as relevant to contemporary practice. McRae's Orthopaedic Trauma and Emergency Fracture Management utilises a detailed descriptive and didactic style, alongside a wealth of illustrations all completely redrawn for this book. The first section on general principles in orthopaedic trauma deals with basic terminology and classificat...
