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Notebook
College Ruled Color Paperback. Size: 6 inches x 9 inches. 55 sheets (110 pages for writing). Eric Bertrand Bailly Pronunciation B. 157796827842
Getting Digital Done
Today's world is moving at a rapid pace. As technologies improve and markets change, companies need to be able to adapt and transform to meet the demands of their consumers. But the process of "going digital" takes more than a simple change in tech. Sometimes, a complete change of operations is needed. In Getting Digital Done, the author team from dPrism, a leading technology consulting firm, show how any company can enact significant change in their company to implement digital solutions. And as you'll learn, the actual technology is the last thing to consider. Follow along as the authors tell a story of a company struggling to adapt. The CEO consults with dPrism who presents a compelling strategy for digital implementation. Along the way, you'll discover the importance of obtaining buy-in from the people who will deliver the work and, and you'll find a framework for implementing a digital strategy within your own business. By the end of the book, you'll understand the next steps you need to take to undergo a digital transformation. Change isn't easy. But with the right plan, you'll be well prepared to navigate the shifting demands of the modern world.
En Fuite
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Genome Stability and Human Diseases
Since the establishment of the DNA structure researchers have been highly interested in the molecular basis of the inheritance of genes and of genetic disorders. Scientific investigations of the last two decades have shown that, in addition to oncogenic viruses and signalling pathways alterations, genomic instability is important in the development of cancer. This view is supported by the findings that aneuploidy, which results from chromosome instability, is one of the hallmarks of cancer cells. Chromosomal instability also underpins our fundamental principles of understanding tumourigenesis: It thought that cancer arises from the sequential acquisition of genetic alterations in specific ge...
Water Soluble Vitamins
The discovery of vitamins in the early 1900s, their later chemical characterization and the clarification of pivotal metabolic functions are sequential aspects of a brilliant chapter in the history of modern nutritional sciences and medicine. The name, derived from “vital-amines”, indicates their elementary metabolic key functions in human metabolism. Vitamins are truly families of compounds, which include precursors and various free and bound forms, all with individual roles in metabolism and function. A more recent approach therefore searches for the components, the understanding of their roles in physiology and pathology as well as looking for novel pharmacological applications. When ...
20 years of Criminology at the NICC
This book marks the 20th anniversary of the Department of Criminology of the National Institute of Criminalistics and Criminology (NICC). On the occasion of this anniversary, a series of research seminars were organised, during which NICC researchers, practitioners and international experts engaged in a dialogue on several key research themes. They discussed the future of the Department of Criminology and put the work of the NICC into perspective, both nationally and internationally. The results of these exchanges are bundled in this book.
Molecular Mechanisms of Parasite Invasion
All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.
Subcellular Proteomics
This volume summarizes the new developments that made subcellular proteomics a rapidly expanding area. It examines the different levels of subcellular organization and their specific methodologies. In addition, the book includes coverage of systems biology that deals with the integration of the data derived from these different levels to produce a synthetic description of the cell as a system.
A Handbook of Transcription Factors
Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.
