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Using Patient Values and Preferences to Inform the Importance of Health Outcomes in Practice Guideline Development Following the GRADE Approach
Abstract: Background There are diverse opinions and confusion about defining and including patient values and preferences (i.e. the importance people place on the health outcomes) in the guideline development processes. This article aims to provide an overview of a process for systematically incorporating values and preferences in guideline development. Methods In 2013 and 2014, we followed the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to adopt, adapt and develop 226 recommendations in 22 guidelines for the Ministry of Health of the Kingdom of Saudi Arabia. To collect context-specific values and preferences for each recommendation, we performed system...
MultiPluriTrans in Educational Ethnography
Ethnography has established itself as a key strategy of qualitative research in education, because it is so versatile, flexible, and ambiguous. Its growing importance coincides with an increasing diversity of »discovered« educational realities. In the process, many basic assumptions have turned into genuine tasks of research. Where are the places and times of learning, education, and social work to be found? Who are the actors and addressees? How are education and learning performed and enacted? The contributions to this volume discuss the multiple challenges that ethnographic research has to confront when exploring the multimodality, plurality, and translocality of educational realities.
Evidence Gap on Antihyperglycemic Pharmacotherapy in Frail Older Adults
Abstract: Background Although antihyperglycemic pharmacotherapy in frail older adults with type 2 diabetes mellitus (T2DM) is challenging, recommendations from international guidelines are mainly based on indirect evidence from trials not including frail participants. Objective This systematic review investigated the effectiveness and safety of pharmacotherapy in frail older adults with T2DM. Material and methods Randomized (RCT) and non-randomized prospective clinical trials (non-RCT) were searched in three electronic databases (Medline, Embase, Central) up to October 2018. Trials in older adults with T2DM who were assessed as significantly or severely impaired by defined cut-off scores of ...
Research Response to Coronavirus Disease 2019 Needed Better Coordination and Collaboration: a Living Mapping of Registered Trials
Abstract: Objectives Researchers worldwide are actively engaging in research activities to search for preventive and therapeutic interventions against coronavirus disease 2019 (COVID-19). Our aim was to describe the planning of randomized controlled trials (RCTs) in terms of timing related to the course of the COVID-19 epidemic and research question evaluated. Study Design and Setting We performed a living mapping of RCTs registered in the WHO International Clinical Trials Registry Platform. We systematically search the platform every week for all RCTs evaluating preventive interventions and treatments for COVID-19 and created a publicly available interactive mapping tool at https://covid-nm...
GRADE Evidence to Decision (EtD) Frameworks for Adoption, Adaptation, and de Novo Development of Trustworthy Recommendations: GRADE-ADOLOPMENT
Abstract: Background Guideline developers can: (1) adopt existing recommendations from others; (2) adapt existing recommendations to their own context; or (3) create recommendations de novo. Monetary and nonmonetary resources, credibility, maximization of uptake, as well as logical arguments should guide the choice of the approach and processes. Objectives To describe a potentially efficient model for guideline production based on adoption, adaptation, and/or de novo development of recommendations utilizing the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence to Decision (EtD) frameworks. Study Design and Setting We applied the model in a new national guidel...
Perception and Cognition in Language and Culture
Every language has a way of talking about seeing, hearing, smelling, tasting and touching. This can be done through lexical means, and through grammatical evidentials. The studies presented here focus on the experssions of perception and cognition in languages of Africa, Oceania, and South America.
Translation in Cascading Crises
This volume addresses the imperative need for recognizing, exploring, and developing the role of multilingual communication in crisis settings. It is recognized that 'communication is aid' and that access to communication is an undeniable human right in crises. Even where effective and accurate information is available to be distributed, circulated, and broadcast in different ways through an ever-growing array of technologies, too often the language barrier remains in place. From the Philippines to Lebanon via Spain, Italy, Columbia, and the UK, crisis situations occur worldwide, with different cultural reactions and needs everywhere. The contributors of this volume represent a geographical ...
Nomadic Peoples
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I, Claudia
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