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A obra expressa e oferece análises intelectuais e ensinamentos didáticos que representa um esforço coletivo de pesquisadores por meio do ensino, pesquisa e aplicação do conhecimento imersos nas práticas de ensino e aprendizagem. Ressaltam a linguística ao se dedicar ao estudo científico da linguagem, as letras explorando a produção e a interpretação de textos literários, e as artes ao englobar diversas formas de expressão como resultados de estudos e experiências educacionais. Ao longo de sua trajetória, a coletânea explora abordagens diversas e propostas do professor contemporâneo que interage, em certos momentos, com outras disciplinas ao destacar perspectivas e visões únicas dos indivíduos.
This 2002 book is a guide to Italian usage for students who have already acquired the basics of the language and wish to extend their knowledge. Unlike conventional grammars, it gives special attention to those areas of vocabulary and grammar which cause most difficulty to English-speakers. Careful consideration is given throughout to questions of style, register, and politeness which are essential to achieving an appropriate level of formality or informality in writing and speech. It surveys the contemporary linguistic scene in Italy and gives ample space to the new varieties of Italian that are emerging in modern Italy. The influence of the dialects in shaping the development of Italian is also acknowledged. Clear, readable and easy to consult via its two indexes, this is an essential reference for learners seeking access to the finer nuances of the Italian language.
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Una nevicata senza precedenti, una coppia in crisi, una donna svanita nel nulla. Giornali e social media iniziano a parlare dell’«impiegata quarantenne» scomparsa senza lasciare una riga o un indizio. Un amore dolcissimo che diventa veleno. Un noir che graffia l'anima.
First published in 1917 as 'Midwifery', Obstetrics by Ten Teachers is well established as a concise, yet comprehensive, guide within its field. The twentieth edition has been thoroughly updated by a new team of 'teachers', integrating clinical material with the latest scientific developments that underpin patient care. Each chapter is highly structured, with learning objectives, definitions, aetiology, clinical features, investigations, treatments, case histories and key point summaries and additional reading where appropriate. New themes for this edition include 'professionalism' and 'global health' and information specific to both areas is threaded throughout the text. Along with its companion Gynaecology by Ten Teachers the book will continue to provide an accessible 'one stop shop' in obstetrics and gynaecology for a new generation of doctors.
Remarkable achievements in parasitic disease research, both basic and translational, have occurred over the last ten years, and we have incorporated the majority of these into the 6th edition of Parasitic Diseases. We have added over 1,000 new references to document these advances. Innovative work in the laboratory has provided the clinician/research scientist with a much clearer understanding of the mechanisms of pathogenesis. The number of recently discovered interleukins and their cellular networks has completely re-ordered our comprehension of how parasites and our defense system works to produce protection against infection/reinfection, or in some cases, how it becomes subverted by the ...
The inflammasome is a protein complex composed of an intracellular sensor—typically a Nod-like receptor (NLR), the precursor procaspase-1, and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrates, IL-1β and IL-18. The inflammasome has been implicated numerous diseases, and blockade of inflammasome-derived IL-1β has beneficial effects on several of these diseases. Different books have been edited about the biology of inflammasomes and about methods to study, however, the implication of this complex in the different diseases and pathological conditions show the need of a book about the clinical implications and therapeutic optio...
With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survi...
The Third Aegean Conferences Workshop on Complement-Associated Diseases, Animal Models, and Therapeutics convened to discuss progress in complement research as it pertains to human disease pathogenesis and therapeutics. The rapid pace of research and new experimental approaches allow an integrated view of the in vivo biology of the complement system. This book collects writings on the functions of complement, pathophysiology, protein structures, design of complement inhibitors, and complement assays discussed at the conference.