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Sex Hormones in Neurodegenerative Processes and Diseases
The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.
Dopamine
The chemical basis of human emotions has been an exciting aspect in biology. The "feel-good chemical" dopamine (DA) is a hormone and also a neurotransmitter, which performs a critical role in reward and movement control in the brain. DA also performs multiple other functions outside the brain. Regulating unrelated critical biological functions makes this chemical a vital factor for sustaining life in both health and disease. Dopamine - Health and Disease is an endeavour with an objective to understand and appreciate the biological functions of DA in human wellbeing and its potential utility in biomedical research. This effort will supplement scientific and non-scientific communities in stimulating a critical understanding of the biological purpose of "ticklish" DA, which eventually supports the human relentless effort to reduce the burden of disease. As the most exciting molecule,dopamine directly impacts day-to-day life. Anyone who has an eye for health and disease-related concepts will find this book a good read.
Behavioral and Cytological Differences Between Two Parkinson,Äôs Disease Experimental Models
The knowledge about the biochemical and behavioral changes in humans with PD has allowed proposing animal models for its study; however, the results obtained so far have been heterogeneous. Recently, we established a novel PD model in rodents by manganese chloride (MnCl2) and manganese acetate (Mn (OAc)3) mixture inhalation. After inhaling, the rodents presented bilateral loss of SNc dopaminergic neurons. Later, we conclude that the alterations are of dopamine origin since L-DOPA reverted the alterations. After six months, SNc significantly reduced the number of cells, and striatal dopamine content decreased by 71%. The animals had postural instability, action tremor, and akinesia; these sym...
Parkinson’s Disease - Animal Models, Current Therapies and Clinical Trials
Despite being described about 200 years ago, the pathophysiology of Parkinson’s disease (PD) is not well understood due to its complex etiology and heterogeneity of symptoms and progression. Animal models provide a great opportunity to follow the progression of neurodegeneration and to screen potent therapeutic molecules, knowledge of which can be critical for different levels of clinical trials. Contemporary health technologies are coming in handy to accelerate the pace of developing novel and refined therapeutic strategies for PD. This book, Parkinson’s Disease - Animal Models, Current Therapies and Clinical Trials, provides a comprehensive overview of PD, presenting information on animal models of PD and contemporary therapeutic strategies, health technologies, clinical trials, and their influence on the quality of life of patients with PD.
Análisis teórico y experimental en psicología y salud
“Mente sana en cuerpo sano” es un ideal que se ha promovido por generaciones y que deja en claro la estrecha relación que existe entre la psicología y la salud. Con el fin de abonar al desarrollo del campo del conocimiento sobre la vinculación entre estos dos componentes vitales del ser humano, esta obra presenta diversos trabajos teóricos y experimentales contemporáneos desarrollados en México en el campo de la psicología conductual. Los autores comparten tanto sus reflexiones, análisis y metodologías, como los conocimientos específicos, para que los aprovechen otros investigadores, académicos y estudiantes, tanto de pregrado como de posgrado, así como los profesionales de la salud, y de esta manera se puedan generar orientaciones novedosas en los procesos de diagnóstico e intervención para enfermedades concretas o problemas de salud socialmente significativos, como la adicción a las drogas, el mal de Parkinson o los trastornos alimenticios, a la par de favorecer el desarrollo de modelos experimentales y teóricos en esta disciplina. (ITESO)
The Magic of Melatonin
Everything you need to know about the sleep-regulating hormone melatonin! We've always been told maintaining a healthy sleep cycle is of utmost importance to your day-to-day health. But have we ever been told why? Anyone familiar with chronobiology (the science of natural physiological rhythms) knows that the hormone melatonin is the foundation hormone for the circadian rhythm research. In fact, melatonin and sleep research is one of the most fundamental and best-known rhythms in the human body. Disturbance of the melatonin cycle due to any reason interferes with the sleep/wake cycle, which ultimately leads to a number of other neurobehavioral and psychological problems. Due to the widesprea...
La educación a distancia en la UNAM
El horizonte de la educación a distancia en la sociedad del conocimiento y la interacción es extenso ofrece al mismo tiempo oportunidades importantes y riesgos reales que se deben afronta con carácter y decisión (UNESCO, 2003). Uno de estos cambios que implica oportunidades y riesgos es la imperiosa necesidad de una transformación radical en la administración y gestión de los sistemas de educación a distancia en línea. La administración actual de dichos sistemas ha estado en manos por lo regular de personas que han actuado de buena fe, pero que en algunos casos con conocimientos tecnológicos rudimentarios de cómo utilizar las TICS para liberar totalmente en línea la educación a...
Multiquark Hadrons
A comprehensive summary of current research into multiquark hadrons, describing them in terms of constituent quarks, gluons and compact diquarks.
The Story of Cuba
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