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Clássicos em Doença de Chagas
Este admirável volume reuniu especialistas de diversos campos do conhecimento para comentar a importância de 15 artigos clássicos associados à descoberta científica de Carlos Chagas, que completou cem anos em 2009. A obra indica novas diretrizes e os desafios que ainda cercam a doença na atualidade. Organizado por pesquisadoras do Instituto Oswaldo Cruz (IOC/Fiocruz) e da Casa de Oswaldo Cruz (COC/Fiocruz), pela coordenadora de eventos da Fiocruz e por um ex-vice-presidente de pesquisa da instituição, que juntos formaram uma rede para definir quais seriam os principais artigos clássicos que demarcaram o avanço das pesquisas sobre doença de Chagas, o livro contextualiza-os em relação ao centenário e “...assim surge..., coletivo, histórico e atual”, nas palavras de uma das organizadoras.
Advances in TNF Family Research
The biennial TNF-family conferences have been held over the past 20 years, from the time that TNF was cloned. These meetings have followed the enormous progress in this field. Much is now known about the members of the TNF ligand and receptor families, their signaling proteins, mechanisms of action and cellular functions. This volume is the proceedings of the 12th TNF International Conference, held in April 2009. This conference focuses on the physiological, pathophysiological, and medical significance of these important regulators. Sessions at the meeting specifically address their involvement in immunity, development, apoptosis, autoimmunity, cancer, and infection, the normal function and pathology of the neuronal system, as well as major unresolved questions about their mechanisms of action.
American Trypanosomiasis
Chagas disease causes severe socioeconomic impact and a high medical cost in Latin America. WHO and the World Bank consider Chagas disease as the fourth most transmittable disease to have a major impact on public health in Latin America: 120 million persons are potentially exposed, 16 to 18 million of whom are presently infected, causing 45,000 to 50,000 deaths per year. It has been calculated that approximately 2.4 million potential working years are lost because of incapacity and mortality due to the disease, for an annual cost estimated at 20 billion Euros. American Trypanosomiasis provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease: The host: human and mammalian reservoirs The insect vectors: domestic and sylvatic vectors The causative parasite: Trypanosoma cruzi Informs and updates on all the latest developments in the field Contributions from leading authorities and industry experts
Cytokine Gene Polymorphisms in Multifactorial Conditions
The literature on cytokine genetics is vast, so vast that it is now practically beyond the time or logistical constraints of most scientists to successfully keep pace with it. A compilation of the latest research, Cytokine Gene Polymorphisms in Multifactorial Conditions brings together, reviews, and structures up-to-date information on polymorphism
