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Studies in Natural Products Chemistry, Volume 83 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores
A obra oferece introspecções intelectuais e extrospecções didáticas dos autores nas diversas áreas do conhecimento imersos nos fazeres docentes e aprendizagens discentes enquanto resultados de pesquisas e experiências educacionais. Com isso, o estudo exarado nos capítulos, a presente publicação contribui com textos que versam de algum modo, direta ou indiretamente, a educação e o ensino numa perspectiva da teoria ou pela prática pedagógica com a intenção de trazer ideias interdisciplinares e questionamentos para incentivar o debate a respeito do ensino e da aprendizagem. Tudo isso se revela por meio de novos e múltiplos olhares interdisciplinares na educação e articulados pelos conhecimentos teóricos aos práticos, possibilitando ampliar e significar os múltiplos saberes para Pensar e Fazer a Educação.
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Drugs, weapons, migrant labour, women — these are just a few of the many goods that effortlessly cross national borders in this globalized age, often without the knowledge or permission of the nations concerned. How is this remarkable criminal feat managed?From gun runners in the Ukraine, to money launderers in Dubai, cyber criminals in Brazil, racketeers in Japan, and the booming marijuana industry in western Canada, McMafia builds a breathtaking picture of a secret and bloody business.Internationally celebrated writer Misha Glenny crafts a fascinating, highly readable, and impressively well-researched account of the emergence of organized crime as a globalized phenomenon and shows how it...
"This book offers a short, spirited defense of rhetoric and the liberal arts as catalysts for precision, invention, and empathy in today's world. The author, a professor of Shakespeare studies at a liberal arts college and a parent of school-age children, argues that high-stakes testing and a culture of assessment have altered how and what students are taught, as courses across the arts, humanities, and sciences increasingly are set aside to make room for joyless, mechanical reading and math instruction. Students have been robbed of a complete education, their imaginations stunted by this myopic focus on bare literacy and numeracy. Education is about thinking, Newstok argues, rather than the...
Learn how automotive Ethernet is revolutionizing in-car networking from the experts at the core of its development. Providing an in-depth account of automotive Ethernet, from its background and development, to its future prospects, this book is ideal for industry professionals and academics alike.
All-new clinical resource for managing children with developmental and behavioral concerns. Developed by leading experts in developmental and behavioral pediatrics, the all-new AAP Developmental and Behavioral Pediatrics gives one place to turn for expert recommendations to deliver, coordinate, and/or monitor quality developmental/behavioral care within the medical home. The one resource with all the essentials for pediatric primary care providers. Evaluation and care initiation: Interviewing and counseling, Surveillance and screening, Psychoeducational testing, Neurodevelopment.
The rights guaranteed in the First Amendment—including freedom of expression—are among the fundamental touchstones of our democracy. In Speaking Freely, Floyd Abrams, who for over thirty years has been our most eloquent and respected advocate for uncensored expression, recounts some of the major cases of his remarkable career—landmark trials and Supreme Court arguments that have involved key First Amendment protections.With adversaries as diverse as Richard Nixon and Wayne Newton and allies as unlikely as Kenneth Starr, Abrams takes readers behind the scenes to explain his strategies, the ramifications of each decision, and its long-term significance, presenting a clear and compelling look at the law in action.
Thirty-five million Americans are living beyond the age of sixty-five, a twenty-five year increase in life expectancy since 1900. This longevity, once the gift of a few, has become the destiny of many. This time of life is not just about retiring; in fact many who retire return happily to some type of employment. It is a new stage of life filled with its own unique challenges and opportunities. Co-authors Jane Thayer and Peggy Thayer, a mother-daughter team of psychologists, have named this stage of life, 'elderescence.'