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AVALIAÇÃO E A FORMAÇÃO DE PROFESSORES: Teoria e Realidade
Os textos que compõe a organização deste livro foram escritos por acadêmicos(as) de pedagogia, diante de suas vivências, em um contexto social inclusivo e que não ignora as teorias e realidades durante o processo formativos. Os autores foram motivados ao ensino, pesquisa e extensão constituintes da Faculdade de Pedagogia da Universidade Federal do Pará, campus Castanhal para produção e divulgação científica interna e externas. Esperamos oferecer aos leitores reflexões e a compreensão de que avaliação é inclusão, ou seja, um constituinte primordial do ato pedagógico e formativo, bem como, permitir a formação de sujeitos criativos investigativos, ou seja, do Homo creare experimentalis.
Epidemiologic Methods for the Study of Infectious Diseases
This is the first comprehensive text on the methodological issues in epidemiologic research on infectious diseases. It will be an invaluable resource both to students of epidemiology and to established researchers. The authors address such questions as: What needs to be considered when enrolling participants in a study of sexually transmitted diseases? What are common sources of measurement error in population-based studies of respiratory infections? What are some sources of existing data for epidemiologic studies of infectious diseases? Answers to these and many other related questions can be found in this well-organized, comprehensive and authoritative volume - the first to thoroughly addr...
Drug Discovery and Development, Volume 1
From first principles to real-world applications -- here is the first comprehensive guide to drug discovery and development Modern drug discovery and development require the collaborative efforts of specialists in a broadarray of scientific, technical, and business disciplines--from biochemistry to molecular biology, organic chemistry to medicinal chemistry, pharmacology to marketing. Yet surprisingly, until now, there were no authoritative references offering a complete, fully integrated picture of the process. The only comprehensive guide of its kind, this groundbreaking two-volume resource provides an overview of the entire sequence of operations involved in drug discovery and development...
Human Milk and Lactation
Human milk is uniquely tailored to meet infants’ specific nutritional requirements. However, it is more than just “milk”. This dynamic and bioactive fluid allows mother–infant signalling over lactation, guiding the infant in the developmental and physiological processes. It exerts protection and life-long biological effects, playing a crucial role in promoting healthy growth and optimal cognitive development. The latest scientific advances have provided insight into different components of human milk and their dynamic changes over time. However, the complexity of human milk composition and the synergistic mechanisms responsible for its beneficial health effects have not yet been unra...
Target Discovery and Validation
The modern drug developers? guide for making informed choices among the diverse target identification methods Target Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, and computational methods. Additionally, the book highlights techologies that are applicable to ?difficult? targets and drugs directed at multiple targets, including chemoproteomics, activity-based protein profiling, pathway mapping, genome-wide association studies, and array-based profiling. Thro...
Cultural Diversity in Organizations
--Cultural Diversity in Organizations provides the most comprehensive base of knowledge yet assembled on the topic of cultural diversity. It captures the enormous complexity of the topic by examining diversity on three levels of analysis-individual, group, and organizational and addressing diversity from multiple perspectives-theory, research, and practice. Winner of the 1994 George R. Terry Book Award given by the National Academy of Management to "the book judged to have made the most outstanding contribution to the advancement of management knowle
The Czar's Madman
Timo von Bock's release by the Czar from nine years' incarceration does not spell the end of the Baron's troubles: he is confined to his Livonian estate to live under the constant eye of police informers planted among his own household, and is subjected to endless humiliations. It is claimed that he is a madman and in need of "protection:" a man would need to be insane, after all, to have taken a Czar at his word when asked for a candid appraisal of the state's infirmities. From the year of his release from prison and return to his wife Eeva, a woman of peasant stock to whom, with her brother Jakob, he has given a solid education, the Baron's life is recorded in a secret journal by this same...
Plant Resistance to Viruses
Concern about the environmental consequences of the widespread use of pesticides has increased, and evidence of pesticide-resistant virus vectors have continued to emerge. This volume presents a timely survey of the mechanisms of plant resistance and examines current developments in breeding for resistance, with particular emphasis on advances in genetic engineering which allow for the incorporation of viral genetic material into plants. Discusses the mechanisms of innate resistance in strains of tobacco, tomato, and cowpea; various aspects of induced resistance, including the characterization and roles of the pathogenesis-related proteins; antiviral substances and their comparison with interferon; and cross-protection between plant virus strains. Also presents several papers which evaluate the status of genetic engineering as it relates to breeding resistant plants. Among these are discussions of the potential use of plant viruses as gene vectors, gene coding for viral coat protein, satellite RNA, and antisense RNA, and practical issues such as the durability of resistant crop plants in the field.
Kinase Drug Discovery
Kinase drug discovery remains an area of significant interest across academia and in the pharmaceutical industry. There are now around 13 FDA approved small molecule drugs which target kinases and many more compounds in various stages of clinical development. Although there have been a number of reviews/publications on kinase research, this book fills a gap in the literature by considering the current and future opportunities and challenges in targeting this important family of enzymes. The book is forward-looking and identifies a number of hot topics and key areas for kinase drug discovery over the coming years. It includes contributions from highly respected authors with a combined experie...
The World Health Organization
A history of the World Health Organization, covering major achievements in its seventy years while also highlighting the organization's internal tensions. This account by three leading historians of medicine examines how well the organization has pursued its aim of everyone, everywhere attaining the highest possible level of health.
