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Innovative 3D models for Understanding Mechanisms underlying Lung Diseases: Powerful Tools for Translational Research
The mechanisms underlying acute and chronic lung diseases are complex, reflecting the interplay between multiple cell types, their microenvironment and exogenous challenges. While traditional in vitro cell culture approaches have been instrumental in advancing our knowledge of cellular signalling and function, they typically lack the cell-cell and cell-matrix interactions that define the niche in which lung cell and tissue functions emerge. Implementing in vivo and ex vivo three-dimensional (3D) models more realistically mimicking the in vivo cell-extracellular matrix (ECM) crosstalk should facilitate a considerable leap towards better understanding lung diseases and thus in investigating ne...
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A Genealogy of the Meisser Family (Meiser, Miser, Mizar, Mizer, Myser)
Johan Jurg Meisser was a German Palatine who immigrated to America in 1709, settling in Pennsylvania. Descendants lived in Pennsylvania, California, Nebraska, Ohio, Indiana, Kansas, Tennessee, Michigan, Missouri, Alabama, Arkansas, Texas, Illinois, Wyoming, Idaho, Wisconsin, Oklahoma, New York, and elsewhere.
