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The pathogenic microbiome is the community of microorganisms that live in humans or animals and cause disease. These microorganisms include bacteria, viruses, fungi, protozoa, etc. They usually live in the host's skin, mouth, intestinal tract, genitourinary tract, etc. Normally, there is a state of equilibrium between the host and these microorganisms, but when this equilibrium is disturbed, these microorganisms become the pathogenic microbiome and cause disease. To advance the field of microbiome research, artificial intelligence methods, especially machine learning and deep learning, have recently been used as important tools due to their powerful predictive and informative potential. Clas...
An increasing number of studies suggest that the abnormality of substance and energy metabolism of tumor cells is among the unsolved complex pathological mechanism problems in malignant tumor. The abnormal metabolism of substance and energy in tumor cells is not only the cause of occurrence and development of malignant tumors, but also the concrete embodiment of their pathological changes. Substance and energy metabolism of tumor cells largely depends on neuroendocrine regulation, so it is of great scientific and clinical significance to analyze its regulatory mechanism. The imbalance of material and energy metabolism of tumor cells is one of the major causes for the occurrence and developme...
With contributed papers from the 2011 Materials Science and Technology symposia, this is a useful one-stop resource for understanding the most important issues in advances in the synthesis, processing, and applications of nanostructures. Logically organized and carefully selected, the articles cover the themes of the symposia: Nanotechnology for Energy, Healthcare and Industry; Controlled Synthesis Processing and Applications of Structural and Functional Nanomaterials; and Synthesis, Properties, and Applications of Noble Metal Nanostructures. A must for academics in mechanical and chemical engineering, materials and or ceramics, and chemistry.
This book contains 17 papers from the Controlled Processing of Nanoparticle-based Materials and Nanostructured Films; Nanotechnology for Energy, Healthcare, and Industry; and Nanolaminated Ternary Carbides and Nitrides (MAX Phases) symposia held during the 2010 Materials Science and Technology (MS&T'10) meeting, October 17-21, 2010, Houston, Texas. Topics include: Direct Manufacturing; Low Dimension Nanomaterials; Processing and Sintering; Thin Films; Nanolaminated Ternary Carbides and Nitrides (MAX Phases); and Novel Nanomaterial Approaches.
Diabetic foot is a serious complication of diabetes worldwide. The etiology of diabetic foot is quite complex due to its multifactorial nature. Diabetic neuropathy, peripheral artery disease, foot deformity, high blood glucose and secondary infection all can contribute to diabetic foot ulceration and gangrene, sometimes resulting in minor or major amputations. Several risk factors including old age, long-term diabetes, smoking, foot deformity, and ischemia have been identified in diabetic foot. Many diagnostic methods are used for early-stage diabetic neuropathy and peripheral arterial disease, such as pulse wave, ankle-brachial artery ratio, Sudoscan, gait analysis, etc. Due to the high glucose environment, metabolic disorder, ischemia and peripheral neuropathy, diabetic foot ulcer is much more difficult to heal than common traumatic wounds. Therefore, in addition to existing treatments, new methods or techniques are still needed to improve wound healing. We also expect to find novel pathways to elucidate the complicated mechanisms involved in diabetic foot and diabetic wound healing.