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The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Ev...
Dear Academicians, Readers and Educators, We are pleased to present the issue of the International Journal of Secondary Metabolite as a special issue entitled ‘I. International Congress on Medicinal and Aromatic Plants - “Natural And Healthy Life”’. This special issue contains some of scientific studies presented in the congress. Hosting the I. International Medical and Aromatic Plant Congress, held in Konya on 9-12 May 2017, by the coorperation T.R. Ministry of Forestry and Water Affairs, General Directorate of Forestry and Necmettin Erbakan University was a great honor for us. The total number of abstract submission for the congress was 1923. After the scientific evaluation, 85 abs...
The Ottoman lands, which extended from modern Hungary to the Arabian peninsula, were home to a vast population with a rich variety of cultures. The Ottoman World is the first primary source reader to bring a wide and diverse set of voices across Ottoman society into the classroom. Written in many languages—not only Ottoman Turkish but also Arabic, Armenian, Greek, Hebrew, Italian, and Persian—these texts, here translated, span the extent of the early modern Ottoman empire, from the 1450s to 1700. Instructors are supplied with narratives conveying the lived experiences of individuals through texts that highlight human variety and accelerate a trend away from a state-centric approach to Ottoman history. In addition, samples from court registers, legends, biographical accounts, hagiographies, short stories, witty anecdotes, jokes, and lampoons provide exciting glimpses into popular mindsets in Ottoman society. By reflecting new directions in the scholarship with an innovative choice of texts, this collection provides a vital resource for teachers and students.
Jerusalem is a city with a singular nature. Home to three religions, it contains spiritual meaning for people the world over; it is at once a tourist destination and a location with a complex political reality. Tourism, therefore, is an integral part of Jerusalem’s development and its political conflicts. The book traces tourism and pilgrimage to Jerusalem from the late Ottoman era, through the British Mandate, during the period of the divided city, and to the reunification of the city under Israeli rule. Throughout, the city’s evolution is shown to be intertwined with its tourist industry, as tourist sites, accommodations, infrastructure, and services transform the city’s structures a...
Accurate and exhaustive, this book provides a wide overview of the current knowledge on phenotypes, mechanisms and treatment of autism spectrum disorders. It covers topics on diagnostic issues, comorbid conditions and therapeutic strategies along with a detailed discussion on the actual understanding of the pathophysiology of autism disorders. More specifically, this book reviews in detail the current knowledge on the comorbidity between mental and medical disorders, describes abnormal cognitive and social development and gives a thorough overview on genetic as well as brain imaging abnormalities observed in autism spectrum disorders. In addition, the current literature on environmental risk...
This book, combining and updating two previous editions, is a unique source of information on the diagnosis, treatment, and follow-up of metabolic diseases. The clinical and laboratory data characteristic of rare metabolic conditions can be bewildering for both clinicians and laboratory personnel. Reference laboratory data are scattered, and clinical descriptions may be obscure. The Physician’s Guide documents the features of more than five hundred conditions, grouped according to type of disorder, organ system affected (e.g. liver, kidney, etc) or phenotype (e.g. neurological, hepatic, etc). Relevant clinical findings are provided and pathological values for diagnostic metabolites highlighted. Guidance on appropriate biochemical genetic testing is provided. Established experimental therapeutic protocols are described, with recommendations on follow-up and monitoring. The authors are acknowledged experts, and the book will be a valuable desk reference for all who deal with inherited metabolic diseases.
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