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Abstract: Oral health is maintained by a healthy microbiome, which can be monitored by state-of-the art diagnostics. Therefore, this study evaluated the presence and quantity of ten oral disease-associated taxa (P. gingivalis, T. forsythia, T. denticola, F. nucleatum, C. rectus, P. intermedia, A. actinomycetemcomitans, S. mutans, S. sobrinus, oral associated Lactobacilli) in saliva and their clinical status association in 214 individuals. Upon clinical examination, study subjects were grouped into healthy, caries and periodontitis and their saliva was collected. A highly specific point-of-care compatible dual color qPCR assay was developed and used to study the above-mentioned bacteria of interest in the collected saliva. Assay performance was compared to a commercially available microbial reference test. Eight out of ten taxa that were investigated during this study were strong discriminators between the periodontitis and healthy groups: C. rectus, T. forsythia, P. gingivalis, S. mutans, F. nucleatum, T. denticola, P. intermedia and oral Lactobacilli (p
Abstract: This study investigated the potential of salivary bacterial and protein markers for evaluating the disease status in healthy individuals or patients with gingivitis or caries. Saliva samples from caries- and gingivitis-free individuals (n = 18), patients with gingivitis (n = 17), or patients with deep caries lesions (n = 38) were collected and analyzed for 44 candidate biomarkers (cytokines, chemokines, growth factors, matrix metalloproteinases, a metallopeptidase inhibitor, proteolytic enzymes, and selected oral bacteria). The resulting data were subjected to principal component analysis and used as a training set for random forest (RF) modeling. This computational analysis reveal...
Tony Locker et son club d'amis ont une obsession très particulière, le reniflage des dessous féminins, et ils font le buzz sur le Net ! Je m’appelle Tony Locker. C’est mon « nom de scène », bien sûr. Je suis branché cul. Ça tombe bien, vous aussi ! Il paraît que je suis sex addict. Nous ne sommes donc pas si différents, vous et moi. En fait, je suis juste un renifleur de petites culottes. C’est dégoûtant, pensez-vous ? Je trouve cette passion plutôt excitante et je ne suis pas le seul. Avec mes amis obsédés, nous avons fait le buzz sur le Net, ce qui a bien sûr outré les bien-pensants si propres sur eux qui nous ont dans le nez, offusqués par nos trips de petits dess...
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The purpose of this book is to present a synopsis of what is known about substances that have toxic properties injurious to the eyes, disturbing to vision, or affecting eyes in other unwanted ways. The coverage is truly comprehensive, encompassing local and systemic, acute and chronic, human and veterinary toxicology of the eye. The text summarizes mechanisms of injury, treatments, and other relevant knowledge for more than 3000 alphabetized substances - essentially all those on which public information is available. Also described are systemic side effects of ophthalmologic drugs, treatment of chemical burns of the eyes, and testing methods and species specificity for toxic effects on the eyes. Facilitating access to this prodigious amount of information is a large index that cross-references substances and effects, including numerous synonyms. This monumental work is a truly definitive text and a highly useful reference book that should be available to every ophthalmologist, emergency room, and medical library.
Été 1977, Liverpool Football Club. Un gardien qui n’a jamais encaissé le moindre but. Un gardien invincible. Il affronte l’immense Johan Cruyff, qui a bien l’intention de le battre. Il s’affronte surtout lui-même. Un match de football ? Le grand match de la vie avant tout. Ou quand invincible ne signifie pas forcément invulnérable. À PROPOS DE L'AUTEUR Le journaliste Joël Jenzer, déjà auteur de romans, s’illustre ici avec succès dans un nouveau registre. Dans la tête d’un gardien invincible, il nous tient en haleine au fil des minutes de cette rencontre mythique.
Vol. 6 includes "Gesamtregister zur Familiengeschichtlichen Bibliographie 1897-1937, und zur Heraldischen Bibliographie."
Kindes- und Erwachsenenschutz ist gesellschaftlich brisant, weil er dem Staat Eingriffe in die Persönlichkeitsrechte der betroffenen Eltern bzw. der schutzbedürftigen Personen erlaubt. Umso wichtiger ist es, dass die Interventionen rechtlich und (sozialarbeits-)methodisch korrekt erfolgen. Das Handbuch bietet eine Praxisanleitung für Behördenmitglieder, Beiständinnen und Beistände sowie Fachkräfte im Kindes- und Erwachsenenschutz. Dabei werden rechtlich und methodisch relevante Aspekte von interdisziplinären Teams aus ausgewiesenen und erfahrenen Juristinnen und Juristen sowie Sozialarbeitenden kompakt und vertieft erläutert. Das Handbuch ist somit ein unverzichtbares Standardwerk f...
Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.