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Bioética não é confortável. Confortável são os costumes e os hábitos. A bioética aponta incoerências e questiona costumes, alguns nos quais antes sequer havíamos percebido que havia um por quê de fazer daquele jeito. Desde os primeiros relatos de Ética de que temos notícias, desde a época de Sócrates (o filósofo, não o jogador, que por sinal, também questionava), estas perguntas têm feito seu papel de trazer novas reflexões, novos debates, novos diálogos, novos consensos e entre trancos e barrancos, a despeito das injustiças e das tragédias, ao longo dos séculos seguimos com uma melhoria discreta e contínua na nossa história como sociedades. Nem sempre com momentos ...
Parties to cross-border disputes arising anywhere in the vast Portuguese-speaking world – a community of more than 230 million in a space that offers a wide array of investment opportunities across four continents – increasingly seek Portugal as their preferred seat of arbitration. A signatory to all relevant international conventions, Portugal has proven to be an ‘arbitration-friendly’ jurisdiction. This volume is the first and so far only book in English that provides a thorough, in-depth analysis of international arbitration law and practice in Portugal. Its contributing authors are among the most highly regarded legal names in the country, including scholars, arbitrators, and pra...
This compendium is intended to be the first updated review of most of the clinical situations that cancer patients may present. It identifies the clinical picture and the therapeutic orientation, with the degrees of recommendation and evidence, as well as the direct bibliographic reference for each statement. We took a multidisciplinary approach, with the collaboration of 261 authors from 9 countries, 45 hospitals and 19 medical and non-medical specialties. This compendium (IOC 2022) is the result of the effort and innovative spirit of its authors, will be updated every two years. The first international edition of cancer care support based on real world evidence (RWE) contains all the latest news in cancer care support treatment and assigns levels of evidence and grades of recommendation so that the reader can obtain a quick impression and certainty of each of the treatments and strategies presented. The GRADE and OXFORD scales have been used for the levels of evidence.
Society, globally, has entered into what might be called the "service economy." Services now constitute the largest share of GDP in most countries and provide the major source of employment in both developed and developing countries. Services permeate all aspects of peoples’ lives and are becoming inseparable from most aspects of economic activity. "Quality management" has been a dominating managerial practice since World War II. With quality management initially associated with manufacturing industries, one might assume the relevance of quality management might decrease with the emergence of the service economy. To the contrary, the emergence of the service economy strengthened the import...
Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the second of two, builds off the conclusions of the first report and outlines a strategy for hepatitis reduction over time and specific actions to achieve them.
A unique and forward-thinking book that sheds new light on the origins, dynamics, and cosmopolitan culture of the Kongo Kingdom from a cross-disciplinary perspective.
This book presents the complete formulation of a new advanced discretization meshless technique: the Natural Neighbour Radial Point Interpolation Method (NNRPIM). In addition, two of the most popular meshless methods, the EFGM and the RPIM, are fully presented. Being a truly meshless method, the major advantages of the NNRPIM over the FEM and other meshless methods, are the remeshing flexibility and the higher accuracy of the obtained variable field. Using the natural neighbour concept, the NNRPIM permits to determine organically the influence-domain, resembling the cellulae natural behaviour. This innovation permits the analysis of convex boundaries and extremely irregular meshes, which is an advantage in the biomechanical analysis, with no extra computational effort associated. This volume shows how to extend the NNRPIM to the bone tissue remodelling analysis, expecting to contribute with new numerical tools and strategies in order to permit a more efficient numerical biomechanical analysis.