Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Macrophage Activation
Macrophages are the sentinels of the immune system whose role has evolved beyond providing aseptic conditions to homeostasis, immune regulation, development, and behaviour. These cells have varied ontogenetic origins which reflects in their phenotypic and functional heterogeneity. Macrophage functions are fine-tuned by exogenous and endogenous signals and once tweaked, the information is included in their genetic makeup, albeit not indefinitely. Subversion of the macrophage functions is the hallmark of many pathogenic organisms and modulation of macrophage activity is pivotal to many therapeutic strategies. Fascinating and rapid developments in this field have necessitated the maintenance of...
Macrophages in the Pathogenesis of Leprosy
Leprosy is a chronic infectious disease caused by the intracellular pathogen Mycobacterium leprae. The disease may present different clinical forms depending on the immunological status of the host. M. leprae may infect macrophages and Schwann cells, and recent studies have demonstrated that macrophages are fundamental cells for determining the outcome of the disease. Skin lesions from patients with the paucibacillary form of the disease present a predominance of macrophages with a pro-inflammatory phenotype (M1), whereas skin lesions of multibacillary patients present a predominance of anti-inflammatory macrophages (M2). More recently, it was shown that autophagy is responsible for the control of bacillary load in paucibacillary macrophages and that the blockade of autophagy is involved in the onset of acute inflammatory reactional episodes in multibacillary cells. So, strategies that aim to induce autophagy in infected macrophages are promising not only to improve the efficacy of multidrug therapy (MDT) but also to avoid the occurrence of reactional episodes that are responsible for the disabilities observed in leprosy patients.
Poéticas Abertas
None
DANÇA NA ESCOLA: reflexões e ações pedagógicas
A presente obra é fruto de encontros e trocas de experiências de professores e professoras que atuam em universidade, escolas e outros espaços, trabalhando com dança. Encontros são perolas que geram debates e reflexões. O rico material que é produzido nesses momentos deve ser socializado, para que possa constituir em ações pedagógicas com qualidade. A dança está sempre presente na vida do ser humano, desde seus primórdios e permanece se modificando e se transformando toda vez que, corpos descobrem novas formas de se comunicarem e se expressarem pelo movimento. Que as experiências exitosas que autores/as compartilham nessa obra possam ser fermentos para novas propostas de dança na escola.
Anais IV Sehum
Neste caderno de resumos expandidos estão contidos os resultados prévios de 22 das investigações em desenvolvimento, distribuídas nas mais variadas temáticas, dentro das duas linhas: práticas de pesquisa em ensino de humanidades e formação de professores em ensino de humanidades. Os textos aqui organizados referem-se ao IV SEHUM - Seminário de Pesquisa em Ensino de Humanidades, ocorrido em setembro de 2019.
Enfermagem contemporânea
A enfermagem é a ciência que tem como objeto a saúde do ser humano em seus aspectos físicos, psicológicos e sociais. Em seu âmbito de atuação abrange os cuidados voltados à prevenção, promoção e recuperação da saúde, em diferentes níveis de atenção. Essa coletânea reúne pesquisas científicas que retratam a enfermagem em diferentes perspectivas. Juntas, refletem a vasta dimensão que forma os campos de atuação do enfermeiro.
Food Science and Technology
This brand new comprehensive text and reference book is designed to cover all the essential elements of food science and technology, including all core aspects of major food science and technology degree programs being taught worldwide. Food Science and Technology, supported by the International Union of Food Science and Technology comprises 21 chapters, carefully written in a user-friendly style by 30 eminent industry experts, teachers and researchers from across the world. All authors are recognised experts in their respective fields, and together represent some of the world’s leading universities and international food science and technology organisations. Expertly drawn together, produ...
Strength and Conditioning for Team Sports
This text introduces the core science underpinning strength and conditioning regimes and explores innovative new approaches combining the best of applied physiology, biomechanics, sports medicine and coaching science.
